Title Parasites and allergy / Monique Capron, Franc̦ois Trottein (eds.)

Published Basel ; London ; New York : Karger, ©2006

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Description 1 online resource (xii, 201 pages) : illustrations Series Chemical immunology and allergy, 1660-2242 ; v. 90 Chemical immunology and allergy ; v. 90. 1660-2242 Contents Helminth-induced immunoregulation of an allergic response to food -- The mutual influence of nematode infection and allergy -- Human schistosomiasis decreases immune responses to allergens and clinical manifestations of asthma -- Proteases in helminth-and allergen-induced inflammatory responses -- Mechanisms underlying helminth-induced Th2 polarization: default, negative or positive pathways? -- Regulation of dendritic cell function by pathogen-derived molecules plays a key role in dictating the outcome of the adaptive immune response -- Glycans modulate immune responses in helminth infections and allergy -- Role of the natural killer T lymphocytes in Th2 responses during allergic asthma and helminth parasitic diseases -- The mast cell and gut nematodes: damage and defence -- Basophils, basophilia and helminth infections -- Innate, adaptive and regulatory responses in schistosomiasis: relationship to allergy -- Regulatory t cells induced by parasites and the modulation of allergic responses Summary The inverse correlation between allergic diseases and helminth infections has been debated for over 30 years. It was initially assumed that the underlying mechanism is an imbalance between Th1 and Th2 responses that, as a result of reduced exposure to Th1-inducing infectious pathogens, has tipped to allergic Th2 responses. It has only recently been clearly demonstrated that helminth infections have negative effects on allergic disease manifestation. This was shown to be consistent with the activity of regulatory cell populations, which control the effector mechanisms of both Th1 and Th2. In th Bibliography Includes bibliographical references and indexes Notes Print version record Subject Allergy -- Pathogenesis Helminthiasis. Helminths. Nematodes. Immune response. Hypersensitivity -- parasitology Helminthiasis Helminths Nematoda Helminthiasis -- immunology Helminths -- immunology Th1 Cells -- immunology Th2 Cells -- immunology MEDICAL -- Immunology. HEALTH & FITNESS -- Allergies. HEALTH & FITNESS -- Diseases -- Immune System. Allergy -- Pathogenesis Helminthiasis Helminths Immune response Nematodes Allergie Parasitäre Krankheit Immunreaktion Form Electronic book Author Capron, Monique Trottein, Franc̦ois ISBN 1423796829 9781423796824 3805579748 9783805579742 9783318012514 3318012513

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