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Title Cardiac electrophysiology methods and models / Daniel C. Sigg [and others], editors
Published New York ; London : Springer, ©2010


Description 1 online resource (xiv, 491 pages) : illustrations (some color)
Series 2010 Springer E-Books
Contents Basic cardiac electrophysiology: excitable membranes -- Cardiac action potentials, ion channels, and gap junctions -- Anatomy and physiology of the cardiac conduction system -- The electrocardiogram and clinical cardiac electrophysiology -- Clinical cardiac electrophysiology : an overview of its evolution -- Principles of electrophysiological in vitro measurements -- Cardiac cellular electrophysiological modeling -- Computer modeling of electrical activation : from cellular dynamics to the whole heart -- Detection and measurement of cardiac ion channels -- Cell culture models and methods -- Isolated tissue models -- Isolated heart models -- Small animal models for arrhythmia studies -- Use of large animal models for cardiac electrophysiology studies -- Optical mapping and calcium imaging -- Electrophysiology of single cardiomyocytes : patch clamp and other recording methods -- Invasive electroanatomical mapping and navigation -- Cardiac electrophysiological imaging : solving the inverse problem of electrocardiography -- Traditional electrophysiological mapping -- Multi-channel system for analysis of cardiac rhythmicity and conductivity in vitro -- Cardiac CT/MRI imaging for electrophysiology -- Introduction to translational research -- Clinical perspective : electrophysiology in the young and patients with congenital heart disease
Summary Cardiovascular disease is the major cause of mortality and morbidity in the Western Hemisphere. While significant progress has been made in treating a major sub-category of cardiac disease, arrhythmias, significant unmet needs remain. In particular, every day, thousands of patients die because of arrhythmias in the US alone, and atrial fibrillation is the most common arrhythmia affecting millions of patients in the US alone at a given time. Therefore, there is a public need to continue to develop new and better therapies for arrhythmias. Accordingly, an ever increasing number of biomedical, ph
Bibliography Includes bibliographical references and index
Notes Print version record
In Springer eBooks
Subject Heart -- Electric properties.
Heart -- Diseases -- Treatment.
Digital computer simulation.
Computer simulation.
Electrophysiologic Techniques, Cardiac
Heart Conduction System -- physiopathology
Arrhythmias, Cardiac -- physiopathology
Models, Cardiovascular
Computer Simulation
Electric Stimulation Therapy
MEDICAL -- Physiology.
SCIENCE -- Life Sciences -- Human Anatomy & Physiology.
Heart -- Electric properties.
Heart -- Diseases -- Treatment.
Electrophysiologic Techniques, Cardiac.
Heart Conduction System -- physiopathology.
Arrhythmias, Cardiac -- physiopathology.
Models, Cardiovascular.
Computer simulation.
Digital computer simulation
Computer simulation
Heart -- Diseases -- Treatment
Heart -- Electric properties
Form Electronic book
Author Sigg, Daniel C.
ISBN 9781441966582