| Description |
1 online resource (168 pages) |
| Series |
Modern otology and neurotology |
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Modern otology and neurotology.
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| Contents |
Preface; Contents; Chapter 1: Overview; 1.1 Inner Ear Malformation; 1.1.1 The Eighteenth Century: "Dissection of€the€Temporal Bone by€Mondini (Figs. 1.1 and€1.2)"; 1.1.2 The Nineteenth Century: "Temporal Bone Histology"; 1.1.3 The Twentieth Century: "X-ray and€CT of€Temporal Bone"; 1.1.4 The Twenty-First Century: "High-Resolution CT and€MRI of€the€Temporal Bone"; 1.2 Cochlear Nerve Deficiency (CND); References; Chapter 2: Embryology of€Inner Ear and€Its Malformation; 2.1 Anatomical Development of€the€Cochlea and€Auditory System |
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2.1.1 Development of€the€Cochlea and€Myelination of€the€Auditory System2.1.2 Inner Ear Malformation and€Arrest of€Development of€the€Inner Ear; 2.1.3 Development of€the€Central Auditory Pathway; 2.1.4 As Developmental Arrest of€the€Inner Ear, Common Cavity, and€Cochlear Nerve Deficiency May Occur; 2.1.5 Conduction Speed of€Nerve Impulse Before€and€After Myelination; References; Chapter 3: Embryology of€Cochlear Nerve and€Its Deficiency; 3.1 Introduction; 3.2 Embryology; 3.2.1 First Trimester; 3.2.2 Second Trimester; 3.2.3 Third Trimester; 3.2.4 Summary; 3.3 Cochlear Nerve Deficiency |
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3.4 ConclusionReferences; Chapter 4: Morphology, Development, and€Neurotrophic Regulation of€Cochlear Afferent Innervation; 4.1 Introduction; 4.2 Morphology of€SGNs and€Their Neural Connection; 4.3 Development of€SGNs; 4.3.1 Neurogenesis; 4.3.2 Cell Death in€SGNs; 4.3.3 Postnatal Rearrangement of€Cochlear Afferent Innervation; 4.4 Neurotrophic Factors and€SGNs; 4.4.1 Expression of€Neurotrophins and€Their Receptors in€the€Cochlea; 4.4.2 Neurotrophic Support for€SGN Survival in€Embryonic Development; 4.4.3 Other Neurotrophic Factors Involved in€the€Development of€Cochlear Innervation |
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4.4.4 Neurotrophic Factors Promote Survival and€Neuritogenesis of€SGNs In€Vitro4.4.5 Damage of€the€Organ of€Corti and€Secondary Degeneration of€SGNs; 4.4.6 Therapeutic Potential of€Neurotrophic Factors in€Cochlear Implant Therapy; References; Chapter 5: Genetics of€Inner Ear Malformation and€Cochlear Nerve Deficiency; 5.1 Introduction; 5.2 Nonsyndromic Hearing Loss; 5.2.1 DFNB4/Pendred Syndrome; 5.2.2 DFN3; 5.3 Syndromic Hearing Loss; 5.3.1 Waardenburg Syndrome; 5.3.2 BOR Syndrome; 5.3.3 CHARGE Syndrome; 5.3.4 Okihiro Syndrome; 5.3.5 Distal Renal Tubular Acidosis (DRTA) |
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5.4 Chromosomal Disorders Associated with€Hearing Loss5.4.1 Trisomy 21 (Down Syndrome); 5.4.2 Trisomy 18 (Edwards Syndrome); 5.4.3 Trisomy 13 (Patau Syndrome); 5.4.4 22q11.2 Deletion Syndrome (DiGeorge Syndrome); 5.5 Perspective; References; Chapter 6: Classification of€Inner Ear Malformations; 6.1 Introduction; 6.1.1 Complete Labyrinthine Aplasia (CLA, Michel Deformity); 6.1.1.1 Definition and€Radiology; 6.1.1.2 Audiological Findings; 6.1.1.3 Management; 6.1.2 Rudimentary Otocyst; 6.1.2.1 Definition and€Radiology; 6.1.2.2 Management; 6.1.3 Cochlear Aplasia; 6.1.3.1 Definition and€Radiology |
| Summary |
The purpose of this book is to contribute to basic and clinical medical research on cochlear implants for inner ear malformation and cochlear nerve deficiency. Cochlear implantation for children is performed worldwide, and the outcomes concerning speech and hearing acquisition are epoch-making. However, there are some difficulties associated with applying this operative treatment to patients who have complicated inner ear malformations or cochlear nerve deficiencies that have slowed the development of their speech, hearing, and/or sense of balance. The first part of the book outlines the fundamental aspects of inner ear maldevelopment to facilitate readers' understanding of cochlear implantation from the point of view of embryology, morphology, and genetics. In turn, the second part describes current clinical cases and presents successful clinical reports. The book offers a primary resource for otolaryngologists, neurologists, and pediatricians with an interest in this field |
| Notes |
6.1.3.2 Audiological Findings |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Cochlear implants.
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Hearing impaired children.
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Cochlear Implantation
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Cochlear Implants
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MEDICAL -- Surgery -- General.
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Cochlear implants.
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Hearing impaired children.
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| Form |
Electronic book
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| Author |
Kaga, Kimitaka
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| ISBN |
9789811014000 |
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9811014000 |
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9811013993 |
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9789811013997 |
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