Description |
1 online resource (xiv, 178 pages) |
Series |
Milestones in drug therapy |
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Milestones in drug therapy.
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Contents |
Glutamate-based Therapies for Psychiatric Disorders; Introduction; Contents; Contributors; N-Methyl-d-Aspartate (NMDA) Antagonists for the Treatment of Depression; Ionic Glutamate Modulators in Depression (Zinc, Magnesium); Positive Allosteric Modulation of AMPA Receptors: A Novel Potential Antidepressant Therapy; Glutamatergic Modulators for the Treatment of Major Depressive Disorder: Metabotropic Glutamate Receptors; Positive Modulation of AMPA Receptors as a Broad-Spectrum Strategy for Treating Neuropsychiatric Disorders |
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Activation of Group II Metabotropic Glutamate Receptors (mGluR2 and mGluR3) as a Novel Approach for Treatment of SchizophreniamGluR1 Negative Allosteric Modulators: An Alternative Metabotropic Approach for the Treatment of Schizophrenia; Metabotropic Glutamate Receptors as Targets for the Treatment of Drug and Alcohol Dependence; Metabotropic Approaches to Anxiety; Index |
Summary |
Both metabotropic and ionotropic glutamate receptors present attractive 'druggable' targets in treating disorders of the central nervous system. There has been a dramatic shift in the focus of glutamate-based therapies away from neurologic disorders such as stroke and traumatic brain injury to the treatment of psychiatric disorders. This "Milestones in Drug Therapy" volume offers a unique, contemporary overview of preclinical and clinical evidence that modulating glutamatergic tone is an effective means of treating psychiatric disorders ranging from depression and anxiety to schizoph |
Analysis |
geneeskunde |
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medicine |
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volksgezondheid |
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public health |
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farmacologie |
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pharmacology |
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toxicologie |
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toxicology |
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psychiatrie |
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psychiatry |
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neurowetenschap |
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neuroscience |
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Medicine (General) |
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Geneeskunde (algemeen) |
Bibliography |
Includes bibliographical references and index |
Subject |
Mental illness -- Chemotherapy
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Mental illness -- Treatment.
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Glutamic Acid -- therapeutic use
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Mental Disorders -- drug therapy
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Mental Disorders -- therapy
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MEDICAL -- Psychiatry -- Psychopharmacology.
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Biomédecine.
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Sciences de la vie.
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Mental illness -- Chemotherapy
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Mental illness -- Treatment
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Form |
Electronic book
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Author |
Skolnick, Phil
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ISBN |
9783034602419 |
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3034602413 |
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9783034602402 |
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3034602405 |
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