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Title Glutamate-based therapies for psychiatric disorders / Phil Skolnick, editor
Published Basel : Springer, ©2010

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Description 1 online resource (xiv, 178 pages)
Series Milestones in drug therapy
Milestones in drug therapy.
Contents Glutamate-based Therapies for Psychiatric Disorders; Introduction; Contents; Contributors; N-Methyl-d-Aspartate (NMDA) Antagonists for the Treatment of Depression; Ionic Glutamate Modulators in Depression (Zinc, Magnesium); Positive Allosteric Modulation of AMPA Receptors: A Novel Potential Antidepressant Therapy; Glutamatergic Modulators for the Treatment of Major Depressive Disorder: Metabotropic Glutamate Receptors; Positive Modulation of AMPA Receptors as a Broad-Spectrum Strategy for Treating Neuropsychiatric Disorders
Activation of Group II Metabotropic Glutamate Receptors (mGluR2 and mGluR3) as a Novel Approach for Treatment of SchizophreniamGluR1 Negative Allosteric Modulators: An Alternative Metabotropic Approach for the Treatment of Schizophrenia; Metabotropic Glutamate Receptors as Targets for the Treatment of Drug and Alcohol Dependence; Metabotropic Approaches to Anxiety; Index
Summary Both metabotropic and ionotropic glutamate receptors present attractive 'druggable' targets in treating disorders of the central nervous system. There has been a dramatic shift in the focus of glutamate-based therapies away from neurologic disorders such as stroke and traumatic brain injury to the treatment of psychiatric disorders. This "Milestones in Drug Therapy" volume offers a unique, contemporary overview of preclinical and clinical evidence that modulating glutamatergic tone is an effective means of treating psychiatric disorders ranging from depression and anxiety to schizoph
Analysis geneeskunde
medicine
volksgezondheid
public health
farmacologie
pharmacology
toxicologie
toxicology
psychiatrie
psychiatry
neurowetenschap
neuroscience
Medicine (General)
Geneeskunde (algemeen)
Bibliography Includes bibliographical references and index
Subject Mental illness -- Chemotherapy
Mental illness -- Treatment.
Glutamic Acid -- therapeutic use
Mental Disorders -- drug therapy
Mental Disorders -- therapy
MEDICAL -- Psychiatry -- Psychopharmacology.
Biomédecine.
Sciences de la vie.
Mental illness -- Chemotherapy
Mental illness -- Treatment
Form Electronic book
Author Skolnick, Phil
ISBN 9783034602419
3034602413
9783034602402
3034602405