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Title Toxicology of glutathione transferases / edited by Yogesh C. Awasthi
Published Boca Raton, FL : CRC Taylor & Francis, ©2007


Description 1 online resource (375 pages, 8 unnumbered pages of plates) : illustrations (some color)
Contents Ligandin and Glutathione S-Transferases: Historical Milestones, I. Listowsky and I.M. Arias ; Families of Glutathione Transferases, P. Zimniak and S.P. Singh ; Mammalian Glutathione S-Transferase Genes: Structure and Regulation, I.R. Jowsey and J.D. Hayes ; Combinatorial Protein Chemistry in Three Dimensions: A Paradigm for the Evolution of Glutathione Transferases with Novel Activities, Y. Ivarsson and B. Mannervik ; Substrates and Reaction Mechanisms of GSTs, P. Zimniak ; Specificity of Glutathione S-Transferases in the Glutathione Conjugation of Carcinogenic Diol Epoxides, H. Xiao and S.V. Singh ; GST Polymorphism: Where to Now? Clinical Applications and Functional Analysis, S.L. Holley, A.A. Fryer, W. Carroll, P.R. Hoban, and R.C. Strange ; Glutathione and Glutathione S-Transferases as Targets for Anticancer Drug Development, V.J. Findlay, D.M. Townsend, and K.D. Tew ; Physiological Substrates of Glutathione S-Transferases, R. Sharma, G.A. Shakeel Ansari, and Y.C. Awasthi ; Glutathione S-Transferases as Modulators of Signal Transduction, Y. Yang and Y.C. Awasthi ; Glutathione-Conjugate Transport and Stress-Response Signaling: Role of RLIP76, S.S. Singhal and S. Awasthi ; Glutathione S-Transferases and Oxidative Injury of Cardiovascular Tissues, Y. Yang and P.J. Boor ; Mitochondrial Glutathione S-Transferase Pool in Health and Disease, H. Raza and N.G. Avadhani; Activation of Microsomal Glutathione Transferase 1 in Toxicology, M. Shimoji, Y. Aniya, and R. Morgenstern ; Glutathione S-Transferase Isozyme Composition of Human Tissues, S. Dhanani and Y.C. Awasthi ; Enzymology of Glutathione S-Transferases: Laboratory Methods, S.S. Singhal, K. Drake, S. Yadav, J. Singhal, and S. Awasthi Index
Summary Since the discovery of Glutathione S-Transferase (GST) or Glutathione transferase, studies have probed important questions about its pharmacological and physiological significance. Toxicology of Glutathione Transferases is the only text that details the methods used in GST research. With chapters written by experts who have been involved in all areas of GST research and have actively contributed to the progress of this field, the book describes the role of GSTs in toxicology, focusing on their pharmacologic and physiologic roles and their relevance to biological toxicology. The book
Bibliography Includes bibliographical references and index
Notes English
Print version record
Subject Glutathione transferase.
Biochemical toxicology.
Glutathione Transferase -- toxicity
Glutathione Transferase
Glutathione Transferase -- therapeutic use
Toxicology -- methods
MEDICAL -- Toxicology.
Biochemical toxicology
Glutathione transferase
Form Electronic book
Author Awasthi, Yogesh C
ISBN 9781420004489