| Description |
1 online resource (xii, 350 pages) : illustrations |
| Series |
NATO science series. Series I, Life and behavioural sciences, 1566-7693 ; v. 347 |
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NATO science series. Series I, Life and behavioural sciences ; v. 347. 1566-7693
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| Contents |
Oxidative signaling and glutathione synthesis -- Cell survival and changes in gene expression in cells unable to synthesize glutathione -- Role of glutathione in the regulation of liver metabolism -- Glutathione transport in the endo/sarcoplasmic reticulum -- Role of ascorbate in oxidative protein folding -- Cytophotometric investigations on oscillating thiol-disulfide equilibria and oxidized protein sulfur -- Protection by pantothenic acid against apoptosis and cell damage by oxygen free radicals -- the role of glutathione -- Thiols as major determinants of the total antioxidant capacity -- Enzymes of the thio9l-dependent hydroperoxide metabolism in pathogens as potential drug targets -- Is there a role of glutathione peroxidases in signaling and differentiation? -- Multidrug resistance-associated proteins: export pumps for conjugates with glutathione, glucuronate or sulfate -- Detoxification of eletrophilic compounds by glutathione s-transferase catalysis: determinants of individual response to chemical carcinogens and chemotherapeutic drugs? -- Transcriptional regulation of glutathione s-transferase P1-1 in human leukemia -- Mechanism of [gamma]-glutamyltranspeptidase folding and activation in the endoplasmic reticulum |
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The role of [gamma]-glutamyl transpeptidase in the biosynthesis of glutathione -- Role of [gamma]-glutamyltransferase in the homeostasis of glutathione during oxidative and nitrosative stress -- The importance of gamma-glutamyl transferase in lung glutathione homeostasis and antioxidant defense -- The role of gamma-glutamyltranspeptidase in the metabolism and cytotoxicity of 4-hydroxynonenal-glutathione conjugate: evidence and hypothesis -- [gamma]-glutamyltransferase-dependent prooxidant reactions: a factor in multiple processes -- Serum gamma-glutamyl transpeptidase: a prognostic marker in cardiovascular diseases -- Lipoic acid: a multifunctional antioxidant -- Is glutathione an important neuroprotective effector molecule against amyloid beta toxicity? -- Antioxidants in cancer therapy: is there a rationale to recommend antioxidants during cancer therapy? -- Disulfide exchange in CD4 -- Redox regulation in protein folding and chaperone function -- Reduction of the endoplasmic reticulum accompanies the oxidative damage of diabetes mellitus -- Analytical developments in the assay of intra- and extracellular GSH homeostasis -- Signalling potential and protein modifying ability of physiological thiols -- Redox signaling and the map kinase pathways -- Redox regulation of mitochondrial permeability transition: contrasting effects of lipoic acid and its positively charged analog LA-plus -- Redox state of glutathione and |
| Summary |
This volume contains contributions by some of the leading scientists in the field of thiol oxidation/reduction (redox) biochemistry. It is focused on the biological/pathophysiological implications of newly-discovered functions of cellular thiols, such as glutathione in the first place |
| Notes |
"Published in cooperation with NATO Scientific Affairs Division." |
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"Proceedings of the NATO Advanced Research Workshop on Thiol Metabolism and Redox Regulation of Cellular Functions, 10-13 April 2002, Pisa, Italy"--Title page verso |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212 MiAaHDL |
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Print version record |
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digitized 2010 HathiTrust Digital Library committed to preserve pda MiAaHDL |
| Subject |
Antioxidants -- Congresses
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Thiols -- Physiological effect -- Congresses
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Glutathione -- Physiological effect -- Congresses
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Oxidation-reduction reaction -- Congresses
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Cell respiration -- Congresses
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Oxidation-reduction reaction.
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Cell physiology.
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Glutathione.
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Oxidation-Reduction
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gamma-Glutamyltransferase
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Cell Physiological Phenomena
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Glutathione
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MEDICAL -- Health Risk Assessment.
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Glutathione
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Cell physiology
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Antioxidants
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Cell respiration
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Glutathione -- Physiological effect
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Oxidation-reduction reaction
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Thiols -- Physiological effect
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| Genre/Form |
proceedings (reports)
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Conference papers and proceedings
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Conference papers and proceedings.
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Actes de congrès.
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| Form |
Electronic book
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| Author |
Pompella, Alfonso
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Bánhegyi, Gábor
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Wellman-Rousseau, Maria
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NATO Advanced Research Workshop on Thiol Metabolism and Redox Regulation of Cellular Functions (2002 : Pisa, Italy)
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| LC no. |
2002111980 |
| ISBN |
0585458707 |
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9780585458700 |
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1601294727 |
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9781601294722 |
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9786610505678 |
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6610505675 |
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