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Title Phase II conjugation enzymes and transport systems / edited by Helmut Sies, Lester Packer
Published San Diego, Calif. : Elsevier Academic Press, [2005]
Online access available from:
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Description 1 online resource (xxxix, 695 pages, 28 unnumbered pages of plates) : illustrations
Series Methods in enzymology, 0076-6879 ; v. 400
Methods in enzymology ; v. 400. 0076-6879
Summary This volume on conjugation enzymes and transporters serves to bring together current methods and concepts in an interesting, important and rapidly developing field of cell and systems biology. It focuses on the so-called Phase II enzymes of drug metabolism (xenobiotics), which has important ramifications for endogenous metabolism and nutrition. Also included are aspects on Phase III, transport systems. This volume of Methods in Enzymology presents current knowledge and methodology on glucuronidation, sulfation, acetylation, and transport systems in this field of research. Together with the volumes on Quinones and Quinone Enzymes (volumes 378 and 382), and on Glutathione Transferases and gamma-Glutamyl Transpeptidases (volume 401), the state of knowledge on proteomics and metabolomics of many pathways of (waste) product elimination, enzyme protein induction and gene regulation and feedback control is provided. This volume will help stimulate future investigations and speed the advance of knowledge in systems biology. *A laboratory standard for more than 40 years *Over 400 volumes strong *Also available on <a href="">ScienceDirect</a>
Bibliography Includes bibliographical references and indexes
Subject Biological transport.
Drugs -- Metabolism.
Metabolic conjugation.
Xenobiotics -- Metabolism.
Glucuronosyltransferase -- metabolism.
Acetyltransferases -- metabolism.
Biological Transport -- physiology.
Sulfatases -- metabolism.
Xenobiotics -- metabolism.
Form Electronic book
Author Packer, Lester.
Sies, H. (Helmut), 1942-
ISBN 0121828050 (electronic bk.)
9780121828059 (electronic bk.)
Other Titles Phase two conjugation enzymes and transport systems