| Description |
1 online resource (xviii, 579 pages) : illustrations (some color) |
| Contents |
Foreword; Preface; Contents; Contributors; Introduction; Overview of Chromosomal Instability and Aging Mechanisms; Cellular Senescence; Telomeric Shortening and Replicative Aging; Telomeric Regulation in Eukaryotic Cells; Role of Ku at the Telomere; Chromosomal Instability in Normative Aging; Chromatin, Aging, and Cellular Senescence; Werner Syndrome; Bloom Syndrome: Genetic, Cellular, and Molecular Features as Compared to Werner Syndrome; Molecular Biology of Rothmund-Thomson Syndrome; Hutchinson-Gilford Progeria Syndrome; Ataxia-Telangiectasia; Nijmegen Breakage Syndrome |
| Summary |
This text examines the relationship between DNA damage and repair, cellular senescence, genomic instability and ageing. It includes in-depth discussions of various types of DNA damage, the DNA repair network, and cellular responses to genetic damage |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Aging -- Molecular aspects.
|
|
Chromosomes.
|
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Cells -- Aging.
|
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Aging -- Genetic aspects.
|
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Aging -- genetics
|
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Aging, Premature -- genetics
|
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Chromosomes
|
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Cellular Senescence
|
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Genetic Diseases, Inborn -- genetics
|
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MEDICAL -- Nursing -- Gerontology.
|
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FAMILY & RELATIONSHIPS -- Aging.
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Aging -- Genetic aspects
|
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Aging -- Molecular aspects
|
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Cells -- Aging
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Chromosomes
|
| Form |
Electronic book
|
| Author |
Hisama, Fuki M., 1962-
|
|
Weissman, Sherman M
|
|
Martin, George M., 1927-
|
| LC no. |
2002044497 |
| ISBN |
0824747305 |
|
9780824747305 |
|
9780203911709 |
|
0203911709 |
|
