| Description |
1 online resource (xv, 314 pages) : illustrations (some color) |
| Series |
Drug targeting and delivery ; v. 10 |
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Drug targeting and delivery ; v. 10.
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| Contents |
BOOK COVER; HALF-TITLE; TITLE; COPYRIGHT; DEDICATION; CONTENTS; PREFACE TO THE SERIES; PREFACE; CONTRIBUTORS; 1. PRESENT AND FUTURE STATUS OF GENE THERAPY; 2. EXPRESSION PLASMIDS FOR NON-VIRAL GENE THERAPY; 3. DNA PACKAGING IN NON-VIRAL SYSTEMS; 4. BIOLOGICAL BARRIERS TO GENE TRANSFER; 5. CATIONIC LIPID-BASED GENE DELIVERY SYSTEMS; 6. THERAPEUTIC APPLICATIONS OF LIPID-BASED GENE DELIVERY SYSTEMS; 7. POLYMERIC GENE DELIVERY SYSTEMS FOR IN VIVO GENE THERAPY; 8. POLYCATION-BASED DELIVERY SYSTEMS FOR RECEPTOR-MEDIATED GENE DELIVERY; 9. DNA DELIVERY SYSTEMS BASED ON SYNTHETIC PEPTIDES |
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10. GENE-BASED VACCINES11. INTRAVASCULAR DELIVERY OF NAKED PLASMID DNA; 12. GENE THERAPY CLINICAL TRIALS FOR CYSTIC FIBROSIS: VIRAL AND NON-VIRAL APPROACHES; 13. GENE THERAPY FOR CANCER: STRATEGIES AND REVIEW OF CLINICAL TRIALS; INDEX |
| Summary |
A practical resource for everyone involved in the gene therapy field and in the design of effective gene delivery systems, this volume presents an overview and update of recent advances in the field of non-viral methods for the in vivo transfer of therapeutic genes to biological targets using conventional routes of administration. Methods to control the spatial and temporal modulation of gene function in vivo as well as the level, duration, specificity, and fidelity of gene expression are described. The rational design and the applications of a variety of non-viral gene delivery systems, s |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Gene targeting.
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Genetic vectors.
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Gene therapy.
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Gene therapy -- Methodology
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Genetic vectors -- Therapeutic use
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Gene Targeting
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Genetic Therapy -- methods
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Genetic Vectors
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Genetic Therapy
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Drug Delivery Systems
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Genetic Vectors -- therapeutic use
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HEALTH & FITNESS -- Diseases -- Genetic.
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MEDICAL -- Genetics.
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Gene targeting
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Gene therapy
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Genetic vectors
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| Form |
Electronic book
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| Author |
Rolland, Alain, 1959-
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| ISBN |
0203303814 |
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9780203303818 |
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