Basic principles of gene transfer -- Chemical and physical transfection -- Cell-mediated gene transfer -- Gene transfer using viral vectors -- Gentic manipulation of animals -- Gene targeting in animal cells -- Control of transgene expression -- Transgene behavior -- Additional strategies for gene inactivation -- Applications of gene transfer in animals
Summary
Gene Transfer to Animal Cells provides a comprehensive summary of transformation technology for animal cells. focusing on principles of the methodology but also covering applications. A range of vectors is describes, including YAC constructs