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Subjects (1-2 of 2)
Genes, APC
1

-- See Also Adenomatous Polyposis Coli


A polyposis syndrome due to an autosomal dominant mutation of the APC genes (GENES, APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of affected individuals by early adulthood
2

-- See Also Adenomatous Polyposis Coli Protein


A negative regulator of beta-catenin signaling which is mutant in ADENOMATOUS POLYPOSIS COLI and GARDNER SYNDROME
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