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Title MicroRNA profiling in cancer : a bioinformatics perspective / edited by Yuriy Gusev
Published Singapore : Pan Stanford, ©2010


Description 1 online resource (xii, 257 pages) : color illustrations
Contents 1. Measurement and interpretation of microRNA expression profiles / Bo Curry and Robert Ach -- 2. MicroRNA expression analysis by LNA enhanced microarrays / Rolf Søkilde [and others] -- 3. Analysis and QC for real-time QPCR arrays of human microRNAs / Dirk P. Dittmer [and others] -- 4. Massively parallel microRNA profiling in the haematologic malignancies / Ryan D. Morin [and others] -- 5. Who dunit? microRNAs involved in prostate cancer / Chang Hee Kim -- 6. Intronic microRNA : creation, evolution and regulation / Sailen Barik and Titus Barik -- 7. miRome architechture and genomic instability / Konrad Huppi [and others] -- 8. Interconnection of microRNA and transcription factor-mediated regulatory networks / Yiming Zhou -- 9. Analysis of microRNA profiling data with systems biology tools / Yuriy Gusev [and others] -- 10. Mathematical and computational modeling of post-transcriptional gene regulation by microRNAs / Raya Khanin and Desmond J. Higham
Summary The discovery of microRNAs - a new class of non-coding RNAs - has revolutionized modern biomedical sciences. This book presents advances in the interdisciplinary field of microRNA research of human cancers from a perspective of quantitative sciences: bioinformatics, computational and systems biology and mathematical modeling
Bibliography Includes bibliographical references and index
Notes Yuriy Gusev, PhD, assistant professor in Bioinformatics, Department of Surgery, at the University of Oklahoma Health Sciences Center, is instrumental in the ongoing development and activities of a surgical research facility focused on molecular and cellular studies of human diseases related to surgery. He is responsible for the management of computerized cell imaging and bioinformatics systems for gene expression micro-arrays technologies in Surgical Research Core Facilities as well as the education of residents, postdoctoral fellows, and medical and graduate students
Print version record
Subject Non-coding RNA.
Cancer -- Genetic aspects.
Genetic regulation.
Computational biology.
Neoplasms -- etiology
Neoplasms -- genetics
Computational Biology
Gene Expression Profiling
Gene Expression Regulation, Neoplastic
MicroRNAs -- genetics
RNA, Untranslated
Gene Expression Regulation
MEDICAL -- Oncology.
HEALTH & FITNESS -- Diseases -- Cancer.
MEDICAL / Oncology
SCIENCE / Life Sciences / Genetics & Genomics
SCIENCE / Life Sciences / General
Cancer -- Genetic aspects.
Genetic regulation.
Non-coding RNA.
Genre/Form Electronic books
Form Electronic book
Author Gusev, Yuriy.
ISBN 9789814267540