| Description |
xxvi, 443 pages : illustrations (some color) ; 24 cm |
| Series |
Nucleic acids and molecular biology ; 14 |
|
Nucleic acids and molecular biology ; v. 14
|
| Contents |
Machine derived contents note: A Nomenclature for Restriction Enzymes, DNA Methyltransferases, Homing Endonucleases and Their Genes.- Restriction-Modification Systems as Minimal Forms of Life.- Molecular Phylogenetics of Restriction Endonucleases.- Sliding or Hopping? How Restriction Enzymes Find Their Way on DNA.- The Type I and III Restriction Endonucleases: Structural Elements in Molecular Motors that Process DNA.- The Integration of Recognition and Cleavage : X-Ray Structures of Pre-Transition.- State Complex, Post-Reactive Complex and the DNA-Free Endonuclease.- Structure and Function of EcoRV Endonuclease.- Two of a Kind: BamHI and BglII.- Structure and Function of the Tetrameric Restriction Enzymes.- Structure and Function of Type IIE Restriction Endonucleases.- Analysis of Type II Restriction Endonucleases That Interact with Two Recognition Sites.- The Role of Water in the EcoRI--DNA Binding.- Role of Metal Ions in Promoting DNA Binding and Cleavage by Restriction Endonucleases.- Restriction Endonucleases: Structure of the Conserved Catalytic Core and the Role of Metal Ions in DNA Cleavage.- Protein Engineering of Restriction Enzymes.- Engineering and Applications of Chimeric Nucleases |
| Bibliography |
Includes bibliographical references and index |
| Subject |
Restriction enzymes, DNA.
|
|
Endonucleases.
|
|
Gene amplification.
|
| Author |
Pingoud, A. (Alfred)
|
| LC no. |
2003064952 |
| ISBN |
3540205020 acid-free paper |
|
