An autosomal recessive disorder caused by a deficiency of acid beta-glucosidase (GLUCOSYLCERAMIDASE) leading to intralysosomal accumulation of glycosylceramide mainly in cells of the MONONUCLEAR PHAGOCYTE SYSTEM. The characteristic Gaucher cells, glycosphingolipid-filled HISTIOCYTES, displace normal cells in BONE MARROW and visceral organs causing skeletal deterioration, hepatosplenomegaly, and organ dysfunction. There are several subtypes based on the presence and severity of neurological involvement
An autosomal recessive disorder caused by a deficiency of acid beta-glucosidase (GLUCOSYLCERAMIDASE) leading to intralysosomal accumulation of glycosylceramide mainly in cells of the MONONUCLEAR PHAGOCYTE SYSTEM. The characteristic Gaucher cells, glycosphingolipid-filled HISTIOCYTES, displace normal cells in BONE MARROW and visceral organs causing skeletal deterioration, hepatosplenomegaly, and organ dysfunction. There are several subtypes based on the presence and severity of neurological involvement
Here are entered works on the process of assessing the implications for women and men of any planned action, including legislation, policies or programs, in any field of interest or at any level of government, with the goal of achieving gender equality
Bantu languages -- Grammar, Comparative -- Gbe : Surviving the Middle Passage : the West Africa-Surinam Sprachbund / edited by Pieter Muysken, Norval, Smith, with the assistance of Robert Borges
Gbe languages -- Grammar, Comparative -- Bantu : Surviving the Middle Passage : the West Africa-Surinam Sprachbund / edited by Pieter Muysken, Norval, Smith, with the assistance of Robert Borges
international relations -- EU -- GCC. : An unlikely match or a marriage in the making? EU-GCC relations in a changing security environment / Helle Malmvig
Here are entered works on examinations for courses maintaining A-level standards but containing only half the content of A-level courses taken by students at approximately age eighteen in England, Wales, and countries having educational systems modeled after the British system
Here are entered works on an examination for children over 16 years old in England and Wales that combines aspects of the General Certificate of Education with those of the Certificate of Secondary Education