The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway
Gaspé (Québec) -- Description and travel : Exploring the world. Canada. 13, The Gaspé / executive producers, Jake and Mieke de Boer, John Hamilton ; directed by Giorgio Saturnino ; produced by Brenda & Jakob de Boer ; hosts, Jake de Boer, Mieke de Boer
Gassner, Johann Joseph, 1727-1779. : Exorcism and Enlightenment : Johann Joseph Gassner and the demons of eighteenth-century Germany / H.C. Erik Midelfort
Gast, John, 1772-1837. : Artisans and politics in early nineteenth-century London : John Gast and his times / I. J. Prothero
1979
1
Gästarbetare -- Förenta staterna. : No man's land : Jamaican guestworkers in America and the global history of deportable labor / Cindy Hahamovitch
2011
1
Gasteazoro, Ana Margarita. : Tell Mother I'm in Paradise : Memoirs of a Political Prisoner in El Salvador / Ana Margarita Gasteazoro ; edited by Judy Blankenship and Andrew Wilson ; introduction by Erik Ching
2022
1
Gästebetreuung : Cherishing men from afar : Qing guest ritual and the Macartney Embassy of 1793 / James L. Hevia