| Description |
1 online resource (xxii, 436 pages) : illustrations |
| Series |
Neuromethods ; 24 |
|
Neuromethods ; 24.
|
| Contents |
Models of alcohol consumption using the laboratory rat / Robert B. Stewart and Larry A. Grupp -- Development of an animal model of ethanol abuse: genetic approach / Kalervo Kiianmaa, Petri Hyytia, and John David Sinclair -- Genetic animal models: a user's guide / R. Adron Harris and John C. Crabbe -- Alcohol tolerance: methodological and experimental issues / Anh Dzung Le, S. John Mihic and Peter H. Wu -- Animal models of drug addiction: barbiturates / Michiko Okamoto -- Benzodiazepine tolerance and dependence / Richard G. Lister -- Self-administration of psychomotor stimulants using progressive ratio schedules of reinforcement / David C.S. Roberts and Nicole R. Richardson -- Opiate withdrawal-produced dysphoria: a taste preference conditioning model / Ronald F. Mucha -- Rodent model for nicotine self-administration / William A. Corrigall -- Animal models for assessing hallucinogenic agents / Richard A. Glennon -- Animal models for caffeine exposure in the perinatal period / Ronnie Guillet |
| Summary |
To the Animal Models Volumes This volume describes animal models of drug addiction. Because of increasing public concern over the ethical treatment of animals in research, we felt it incumbent upon us to include this general preface in order to indicate why we think further research using animals is necessary. Animals should only be used when suitable alternatives are not available, and humans can only be experimented upon in severely proscribed circumstances. Alternative procedures using cell or tissue culture are inadequate in any models requiring assessments of behavioral change or of complex in vivo p- cesses. However, when the distress, discomfort, or pain to the animals outweighs the anticipated gains for human welfare, the research is not ethical and should not be carried out. It is imperative that each individual researcher examine his/ her own research from a critical moral standpoint before eng- ing in it, and take into consideration the animals' welfare as well as the anticipated gains. Furthermore, once a decision to p- ceed with research is made, it is the researcher's responsibility to ensure that the animals' welfare is of prime concern in terms of appropriate housing, feeding, and maximum reduction of any uncomfortable or distressing effects of the experimental conditions |
| Bibliography |
Includes bibliographical references and index |
| Notes |
English |
|
Print version record |
| Subject |
Alcoholism -- Animal models
|
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Drug abuse -- Animal models
|
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Diseases -- Animal models.
|
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Drug tolerance.
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Disease Models, Animal
|
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Drug Tolerance
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Ethanol -- pharmacology
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Models, Genetic
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Substance-Related Disorders -- physiopathology
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Drug tolerance
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Diseases -- Animal models
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Alcoholism -- Animal models
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Drug abuse -- Animal models
|
| Genre/Form |
Laboratory manuals.
|
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Manuels de laboratoire.
|
| Form |
Electronic book
|
| Author |
Baker, Glen B., 1947-
|
|
Boulton, A. A. (Alan A.)
|
|
Wu, Peter H.
|
| ISBN |
9781592596294 |
|
1592596290 |
|
