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Title Cellular and molecular physiology of cell volume regulation / edited by Kevin Strange
Published Boca Raton : CRC Press, ©1994


Description 1 online resource (400 pages) : illustrations
Contents Fundamental principles and physiological roles of cell volume regulation -- Principles of cell volume regulation / Kenneth R. Hallows, Philip A. Knauf -- Volume regulation in epithelia: transcellular transport and cross-talk / Luis Reuss, Calvin U. Cotton -- Volume regulation in renal medullary nephron segments / Adam M. Sun, Steven C. Hebert -- Clinical significance of cellular osmoregulation / Michael L. McManus, Kevin B. Churchwell -- Organic osmolytes -- Compatible and counteracting solutes / Paul H. Yancey -- Regulation of cellular amino acid levels / James S. Ballantyne, Mary E. Chamberlin -- Role and regulation of methylamines in the response of cells to osmotic stress / Julia Dragolovich, Sidney K. Pierce -- Regulation of intracellular polyols and sugars in response to osmotic stress / Jeff M. Sands -- Volume sensing and signal transduction -- Cellular signal transduction mechanisms / Thomas Force, Joseph V. Bonventre -- Influence of macromolecular crowding on intracellular association reactions: possible role in volume regulation / Allen P. Minton
(cont) How an epithelial cell swells is a determinant of the signaling pathways that activate RVD / R. John MacLeod -- Protein phosphorylation control in the activity of volume-sensitive transport systems / H. Clive Palfrey -- Stretch-activated ion channels / Henry Sackin -- Cytoskeleton and cell volume regulation / John W. Mills, Erik M. Schwiebert, Bruce A. Stanton -- Role of calcium in the control of volume regulatory transport pathways / J. Kevin Foskett -- Eicosanoids and cell volume regulation / Ian Henry Lambert -- Involvement of a G protein in the shrinkage-induced activation of Na-H exchange in barnacle muscle fibers / Walter F. Boron, Emilia M. Hogan, Bruce A. Davis -- Coordinated regulation of volume-activated transport pathways / John C. Parker -- Role of gene expression in cell volume control -- Regulation of eukaryotic gene expression / Arlyn Garcia-Perez -- Gene expression and osmoregulation in bacteria / Harry H. Yim, Merna R. Villarejo -- Genetic control of osmoregulation in plants / David Rhodes, Yiannis Samaras
(cont) Transcription factors and stress proteins in renal epithelial cell adaptation to hyperosmotic stress / David M. Cohen, Steven R. Gullans -- Aldose reductase gene expression and osmoregulation in mammalian renal cells / Arlyn Garcia-Perez, Joan D. Ferraris -- Molecular regulation of mammalian osmolyte transporters / H. Moo Kwon
Summary The ability to regulate cell volume in the face of osmotic challenge is one of the most fundamental of cellular homeostatic mechanisms. Cellular and Molecular Physiology of Cell Volume Regulation is an integrated collection of articles describing key aspects of cell volume control. The book has been organized around concepts and cellular/molecular processes rather than around mechanisms of volume regulation in specific cell types in order to make it more accessible to a multidisciplinary audience of students, instructors, and researchers
Bibliography Includes bibliographical references and index
Notes Dr. Kevin Strange, Ph. D., is Assistant Professor of Pediatrics in the Division of Nephrology at Children's Hospital, Harvard Medical School, Boston, Massachusetts, and Associate Director of the Renal Research Laboratories., Dr. Strange graduated from the University of California at Davis with a B.S. degree in zoology (summa cum laude) in 1977. He obtained his M.A. and Ph. D. degrees in zoology in 1978 and 1983 from the University of California at Davis and the University of British Columbia, Vancouver, British Columbia, respectively. From 1983 to 1986, he was a research fellow in the Laboratory of Kidney and Electrolyte Metabolism at the National Institutes of Health and became Assistant Professor of Physiology and Biophysics at Wright State University School of Medicine in 1986. He assumed his present position at Children's Hospital and Harvard Medical School in 1990., Dr. Strange is a member of the Society of General Physiologists, the American Physiological Society, the American Society of Nephrology, and the Society for Neuroscience. He has presented a number of invited lectures at international and national scientific meetings and has presented invited talks to the Foster Club at Cambridge University, Cambridge, England, and the Danish Biological Society in Copenhagen, Denmark. In 1993, he was an invited lecturer at the St. Goran's Children's Hospital and the Karolinska Institute in Stockholm, Sweden., Dr. Strange has published more than 30 first or senior authored and numerous coauthored papers. The major research focus in his laboratory is on elucidating the cellular and molecular mechanisms of membrane solute transport and cell volume control in the central nervous system with an emphasis on understanding how these processes relate to various disease states. His research is funded by the National Institutes of Health, the American Heart Association, the National Science Foundation, the American Diabetes Association, and private corporations. He is currently an Established Investigator of the American Heart Association
Print version record
Subject Osmoregulation.
Water-electrolyte balance (Physiology)
Cell physiology.
Water-Electrolyte Balance
Cell Physiological Phenomena
SCIENCE -- Life Sciences -- Cytology.
SCIENCE -- Life Sciences -- Genetics & Genomics.
SCIENCE -- Life Sciences -- General.
Cellules -- Physiologie.
Équilibre hydroélectrolytique (physiologie)
Form Electronic book
Author Strange, Kevin, 1955-
ISBN 9780367812140