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Author Pilch, Richard, author

Title A guide to investigating outbreak origins : nature versus the laboratory / Richard Pilch, Miiles Pomper, Jill Luster, and Filippa Lentzos
Published Monterey, CA : James Martin Center for Nonproliferation Studies, Middlebury Institute for International Studies at Moneterey, 2020
©2020

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Description 1 online resource (26 pages) : color illustrations, color photographs
Series CNS occasional paper ; #49
CNS occasional paper ; #49
Contents Introduction. -- Background. -- Investigating outbreak origins. -- Step 1. Descriptive epidemiology. -- Step 2. Analytical epidemiology. -- (a) Assess the epidemiological triangle. -- (b) Assess the genome. -- Step 3. Additional sample analysis. -- Step 4. Laboratory risk assessment. -- (a) Understand the laboratory's purpose. -- (b) Determine what samples or specimens are present. -- (c) Determine what high risk activities are being performed. -- (d) Determine laboratory safety profile. -- Step 5. On-site laboratory assessment. -- Differentiating deliberate outbreaks. -- Conclusion
Summary COVID-19 has exposed key gaps in the global community's ability to assess infectious disease outbreaks of international concern, in particular the ability to differentiate between natural and laboratory sources of infection. The purpose of this Occasional Paper is to outline a readily adoptable, stepwise methodology to guide the investigation of corresponding outbreak origins, building upon traditional epidemiological principles. We have sought to remain minimally intrusive at all times; however, an increasing level of need-to-know information, site, and personnel access becomes necessary as attention shifts toward potential laboratory sources. Accordingly, we include recommendations to ensure such access under existing international regimes, primarily the World Health Organization (WHO)'s International Health Regulations
Notes "October 2020"--Cover
Bibliography Includes bibliographical references
Notes Online resource; title from PDF cover page (Nonproliferation.org, viewed October 30, 2020)
Subject Epidemics -- Evaluation -- Handbooks, manuals, etc
Genre/Form Handbooks and manuals.
Form Electronic book
Author Pomper, Miles, author
Luster, Jill, author
Lentzos, Filippa, author
James Martin Center for Nonproliferation Studies, publisher.