An ENTEROTOXIN from VIBRIO CHOLERAE. It consists of two major protomers, the heavy (H) or A subunit and the B protomer which consists of 5 light (L) or B subunits. The catalytic A subunit is proteolytically cleaved into fragments A1 and A2. The A1 fragment is a MONO(ADP-RIBOSE) TRANSFERASE. The B protomer binds cholera toxin to intestinal epithelial cells, and facilitates the uptake of the A1 fragment. The A1 catalyzed transfer of ADP-RIBOSE to the alpha subunits of heterotrimeric G PROTEINS activates the production of CYCLIC AMP. Increased levels of cyclic AMP are thought to modulate release of fluid and electrolytes from intestinal crypt cells
Enteroviruses -- Pathogenicity. : Enteroviruses : omics, molecular biology, and control / edited by William T. Jackson (Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, USA) and Carolyn B. Coyne (Department of Pediatrics, University of Pittsburgh, Pittsburgh, PA, USA)
Enterprise Applications COMPUTERS : Office and SharePoint 2010 user's guide : integrating SharePoint with Excel, Outlook, Access and Word / Michael P. Antonovich
Enterprise liability -- United States : Understanding enterprise liability : rethinking tort reform for the Twenty-first Century / Virginia E. Nolan, Edmund Ursin
Here are entered works on sites with parklike surroundings containing office buildings or a mixture of light industrial, high technology, research and development, and general office buildings, often with parking lots, restaurants, and recreation areas
That distinct portion of the institutional, industrial, or economic structure of a country that is controlled or owned by non-governmental, private interests
