| Description |
1 online resource (441 pages) |
| Contents |
Cover; Half Title; Title Page; Copyright Page; Dedication; Contents; Preface; Acknowledgments; Editors; Contributors; Section I Fermentation Microbiology and Biotechnology: Central and Modern Concepts; Chapter 1 Fermentation Microbiology and Biotechnology: An Historical Perspective; 1.1 Fermentation: An Ancient Tradition; 1.2 The Rise of Fermentation Microbiology; 1.3 Developments in Metabolic and Biochemical Engineering; 1.4 Discovery of Antibiotics and Genetic Engineering; 1.5 The Rise and Fall of Single-Cell Protein; 1.6 Fermentation Biotechnology and the Production of Amino Acids |
|
1.7 Biofuels and the "Evolution" of Biorefineries1.8 Impact of Functional Genomics, Proteomics, Metabolomics, and Bio-Informatics on the Scope and Future Prospects of Fermentation Microbiology and Biotechnology; 1.9 Recent Innovations in Systems Biology; 1.10 Recent Innovations in Microbial-Cell Factories; Acknowledgments; References; Chapter 2 Microbiology of Industrial Fermentation: Central and Modern Concepts; 2.1 Introduction; 2.2 Biosynthesis of Biomass During the Course of Fermentation; 2.2.1 Growth Requirements; 2.2.2 The Metabolic Pathways of Central Metabolism |
|
2.2.3 Impact of Growth Rate and Growth Conditions on Cell Composition and Intracellular Fluxes2.2.4 Transport of Nutrients into the Bacterial Cell; 2.2.4.1 During Growth on Rich Media; 2.2.4.2 During Growth on Glucose; 2.2.5 Control of Glycolytic Intermediates Flow into Central Metabolism During Sugar Fermentation; 2.2.6 The Role of ∝-Ketoglutarate in Carbon and Nitrogen Metabolism; 2.2.7 Anaplertic Reactions in Central Metabolism; 2.3 Microbial Growth and Maintenance Requirements During Fermentation; 2.3.1 Mathematical Descriptions of Microbial Growth; 2.3.2 The Growth Cycle |
|
2.3.2.1 The Lag Phase2.3.2.2 Exponential Phase; 2.3.2.3 Stationary Phase; 2.3.2.4 Death and Survival Phase; 2.3.3 Maintenance Energy; 2.3.4 Diauxic Growth; 2.4 Fermentation Balances; 2.4.1 Growth Yield in Relation to Carbon and Energy Contents of Growth Substrates; 2.4.2 Carbon Balance; 2.4.3 Redox Balance; 2.5 Efficiency of Central Metabolism; 2.5.1 Impact of Futile Cycling on the Efficiency of Central Metabolism; 2.5.2 Impact of Metabolite Excretion on the Efficiency of Central Metabolism; 2.6 Continuous Cultivation of Microorganisms; 2.6.1 Types of Continuous Cultures |
| Summary |
Fermentation Microbiology and Biotechnology, 4th Edition explores and illustrates the broad array of metabolic pathways employed for the production of primary and secondary metabolites, as well as biopharmaceuticals. This updated and expanded edition addresses the whole spectrum of fermentation biotechnology, from fermentation kinetics and dynamics to protein and co-factor engineering. It also sheds light on the new strategies employed by industrialist for increasing tolerance and endurance of microorganisms to the accumulation of toxic wastes in microbial-cell factories. The new edition builds upon the fine pedigree of its earlier predecessors and extends the spectrum of the book to reflect the multidisciplinary and buoyant nature of this subject area. Key Features Covers the whole spectrum of the field from fermentation kinetics to control of fermentation and protein engineering. Includes case studies specifically designed to illustrate industrial applications and current state-of-the-art technologies. Presents the contributions of eminent international academics and industrial experts. Offers new chapters addressing: The prospects and the role of bio-fuels refineries, Control of metabolic efflux to product formation in microbial-cell factories and Improving tolerance of microorganisms to toxic byproduct accumulation in the fermentation vessel |
| Notes |
2.8.1.1 History and Background |
|
Print version record |
| Subject |
Microbial biotechnology.
|
|
Fermentation.
|
|
Industrial microbiology.
|
|
Fermentation
|
|
Industrial Microbiology
|
|
SCIENCE -- Life Sciences -- Biology -- Microbiology.
|
|
TECHNOLOGY & ENGINEERING -- Power Resources -- Alternative & Renewable.
|
|
biotechnology.
|
|
engineering and reverse engineering of microorganisms.
|
|
industrial microbiology.
|
|
metabolomics.
|
|
protein engineering.
|
|
Fermentation.
|
|
Industrial microbiology.
|
|
Microbial biotechnology.
|
| Form |
Electronic book
|
| ISBN |
9780429015960 |
|
0429015968 |
|
