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Title Endotoxins : pyrogens, LAL testing and depyrogenation / edited by Kevin L. Williams
Edition 3rd ed
Published New York : Informa Healthcare, ©2007
Online access available from:
ProQuest Ebook Central (owned titles)    View Resource Record  


Description 1 online resource (ix, 419 pages) : illustrations
Series Drugs and the pharmaceutical sciences ; v. 167
Drugs and the pharmaceutical sciences ; v. 167.
Contents Front cover; Preface; Contents; Contributors; Chapter 1. Historical and Emerging Themes; Chapter 2. Endotoxin Relevance and Control Overview; Chapter 3. Fever and the Host Response; Chapter 4. Endotoxin Structure, Function, and Activity; Chapter 5. Descent of Limulus: Arthropoda and the New Biology; Chapter 6. Microbial Biodiversity and Lipopolysaccharide Heterogeneity: from Static to Dynamic Models; Chapter 7. Nonendotoxin Microbial Pyrogens: Lesser Endotoxins and Superantigens; Chapter 8. Risk Assessment in Parenteral Manufacture; Chapter 9. Endotoxin as a Standard
Summary This source expertly examines the discovery, biological structure, control, and continued clarification of endotoxin from a parenteral manufacturing perspective, with in-depth discussion of state-of-the-art technologies involving Limulus amebocyte lysate (LAL) such as assay development, automation, depyrogenation. Completely revised and expanded, this Third Edition contains the knowledge necessary to apply endotoxin testing in the increasingly complex pharmaceutical environment, featuring sections detailing the latest information regarding clinical advances, regulation st
Bibliography Includes bibliographical references and index
Notes Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. MiAaHDL
Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force. WlAbNL
Print version record
digitized 2010 HathiTrust Digital Library committed to preserve pda MiAaHDL
Subject Endotoxins -- Analysis.
Pyrogens -- Analysis
Limulus test.
Drugs -- Microbiology.
Endotoxins -- analysis
Pyrogens -- analysis
Drug Contamination
Infusions, Parenteral -- standards
Limulus Test
MEDICAL -- Toxicology.
Drugs -- Microbiology.
Endotoxins -- Analysis.
Limulus test.
Pyrogens -- Analysis.
Form Electronic book
Author Williams, Kevin L.
ISBN 9781420020595