Title Prions and mad cow disease / edited by Brian K. Nunnally, Ira S. Krull

Published New York : Marcel Dekker, ©2004

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Description 1 online resource (xvi, 428 pages) : illustrations Contents Foreword / David C. Bolton -- 1. Taking Aim at the Transmissible Spongiform Encephalopathies Infectious Agents / Richard I. Carp and Richard J. Kascsak -- 2. Prions, the Protein Hypothesis, and Scientific Revolutions / David C. Bolton -- 3. A Simulation Model for Evaluating the Potential for Spread of Bovine Spongiform Encephalopathy in Animals or to People / Joshua T. Cohen [and others] -- 4. Actions to Prevent Bovine Spongiform Encephalopathy from Entering the United States / Linda A. Detwiler and Burt Pritchett -- 5. Overview of Transmissible Spongiform Encephalopathy in Cervids in the United States / Sam D. Holland -- 6. Bioassays for Prions / Andrew F. Hill, Emmanuel A. Asante, and John Collinge -- 7. Cyclic Amplification of Scrapie Prion Protein : Implications for Diagnosis / Claudio Soto -- 8. The Enfer Transmissible Spongiform Encephalopathies Assay : Chemiluminescent ELISA of Prion Proteins / Riona Sayers -- 9. Sensitive Detection of Prion Proteins by Immunoassay : CEA/Bio-Rad Test / Emmanuel E. Comoy, Jacques Grassi, and Jean-Philipe Deslys -- 10. The Diagnosis of Transmissible Spongiform Encephalopathies Using Differential Extraction and DELFIA / Geoff Barnard and Man-Sun Sy -- 11. In Vivo Diagnosis of Prion Diseases / Ruth Gabizon and Gideon M. Shaked -- 12. Diagnosis of Prion Diseases by Multispectral Techniques / Richard Rubenstein [and others] -- 13. Detection of the Prion Protein in Blood Using a Fluorescence Immunoassay / Mary Jo Schmerr and Andrew Alpert -- 14. Prion Detection and Application to the Safety of Biological Products / Jeanette L.C. Miller [and others] Summary This text recommends possible strategies to prevent bovine spongiform encephalopathy from spreading. It considers cyclic amplification of scrapie prion protein and its implications for diagnosis, as well as the sensitive detection of prion proteins by immunoassay Bibliography Includes bibliographical references and index Notes Print version record Subject Prion diseases. Prions. Bovine spongiform encephalopathy. Encephalopathy, Bovine Spongiform -- prevention & control Encephalopathy, Bovine Spongiform -- etiology Encephalopathy, Bovine Spongiform -- diagnosis Prion Diseases Encephalopathy, Bovine Spongiform Prions -- immunology Prions -- pathogenicity MEDICAL -- Veterinary Medicine -- Food Animal. Bovine spongiform encephalopathy Prion diseases Prions Form Electronic book Author Nunnally, Brian K Krull, Ira S., 1940- ISBN 0824756843 9780824756840 0203912977 9780203912973 9781135525798 113552579X 9781135525743 1135525749 9781135525781 1135525781 9780824740832 0824740831

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