Title Demyelinating disorders of the central nervous system in childhood / edited by Dorothée Chabas, Emmanuelle L. Waubant

Published Cambridge ; New York : Cambridge University Press, 2011

Online access available from: Cambridge Core    View Resource Record

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Description 1 online resource (xiii, 278 pages) : illustrations (some color) Series Cambridge medicine Cambridge medicine (Series) Contents Introduction: historical perspective of pediatric multiple sclerosis and related disorders / Anita L. Belman, Deborah Hertz, and Folker Hanefeld -- Controversies around the current operational definitions of pediatric MS, ADEM and related diseases / Dorothée Chabas, Lauren B. Krupp and Marc Tardieu -- Pediatric MS Diagnosis -- Epidemiology of pediatric multiple sclerosis: incidence, prevalence and susceptibility risk factors / Martino Ruggieri, Immacolata Plasmati and Isabella Simone -- Clinical presentation of multiple sclerosis in children / Angelo Ghezzi and Brenda Banwell -- MRI features of pediatric multiple sclerosis / Bruno P. Soares, Dorothée Chabas and Max Wintermark -- Differential diagnosis of multiple sclerosis and acquired central nervous system demyelinating disorders in children and adolescents / Nancy L. Kuntz and Jonathan Strober -- Pediatric MS course and treatment -- Pediatric multiple sclerosis course and predictive factors / Christel Renoux and Emmanuelle L. Waubant -- Plasma exchange and IV immunoglobulin for acute demyelinating relapses / Khurram Bashir -- Corticosteroids in pediatric multiple sclerosis relapses / Gregory S. Aaen -- Disease modifying therapy and response to first-line treatment in pediatric multiple sclerosis / E. Ann Yeh and Moses Rodriguez -- Treatment of breakthrough disease / Daniela Pohl and Emmanuelle L. Waubant -- Symptomatic therapy in pediatric multiple sclerosis / Sunita Venkateswaran, Susan Bennet and Jayne Ness -- Cognitive dysfunction in pediatric onset multiple sclerosis / Laura J. Julian [and others] -- Living with pediatric multiple sclerosis: patient well-being / Sunny Im-Wang, Maria Milazzo and Ellen M. Mowry -- Pediatric MS Biology -- Pediatric MS: biological presentation and research update / Tanuja Chitnis and Amit Bar-Or -- Genetics of pediatric multiple sclerosis / A.D. Sadovnick and R.Q. Hintzen -- ADEM -- Clinical and biological features of acute disseminated encephalomyelitis / Jin S. Hahn and Silvia Tenembaum -- MRI of acute disseminated encephalomyelitis / Russell C. Dale and Esther Tantsis -- Treatment and prognosis of acute disseminated encephalomyelitis / Amy T. Waldman and Marc Tardieu -- Optic neuritis in children -- Pediatric optic neuritis / Amy T. Waldman and Laura J. Balcer -- Recurrent isolated optic neuritis in the pediatric population / Bianca Weinstock-Guttman and Grant T. Liu -- Acute complete transverse myelitis in children -- What is acute transverse myelitis in children? / Frank S. Pidcock and Guillaume Sébire -- Neuromyelitis in children -- Neuromyelitis optica in children / Andrew McKeon and Timothy Lotze Summary "Although multiple sclerosis and other disorders of myelin formation and repair are most commonly associated with adults, they can also occur in infants, children and adolescents. Up to 5 percent of those with MS experience symptoms before the age of 18, and the number of cases diagnosed is rising. There is a lack of awareness about these diseases in childhood, however, even amongst pediatric neurologists and MS specialists. Demyelinating Disorders of the Central Nervous System in Childhood provides comprehensive coverage of these diseases, highlighting throughout the differences between management in childhood and in adults. With sections dedicated to the diagnosis, course, treatment and biology of pediatric MS, detailed chapters on other childhood demyelinating diseases, including acute disseminated encephomyelitis, optic neuritis, acute complete transverse myelitis and neuromyelitis optica, are also provided. Essential reading for pediatric neurologists and MS specialists, this book will also be valuable reading for adult neurologists and pediatricians"--Provided by publisher Bibliography Includes bibliographical references and index Notes Print version record Subject Demyelination. Encephalomyelitis. Pediatric neurology. Multiple Sclerosis. Adolescent. Child. Demyelinating Autoimmune Diseases, CNS. Diagnosis, Differential. Encephalomyelitis. Infant. Optic Neuritis. Form Electronic book Author Chabas, Dorothée. Waubant, Emmanuelle L. ISBN 051197437X (electronic bk.) 1139077465 (electronic bk.) 9780511974373 (electronic bk.) 9781139077460 (electronic bk.)

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