Title Cardiac electrophysiology methods and models / Daniel C. Sigg [and others], editors

Published New York ; London : Springer, ©2010

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Description 1 online resource (xiv, 491 pages) : illustrations (some color) Series 2010 Springer E-Books Contents Basic cardiac electrophysiology: excitable membranes -- Cardiac action potentials, ion channels, and gap junctions -- Anatomy and physiology of the cardiac conduction system -- The electrocardiogram and clinical cardiac electrophysiology -- Clinical cardiac electrophysiology : an overview of its evolution -- Principles of electrophysiological in vitro measurements -- Cardiac cellular electrophysiological modeling -- Computer modeling of electrical activation : from cellular dynamics to the whole heart -- Detection and measurement of cardiac ion channels -- Cell culture models and methods -- Isolated tissue models -- Isolated heart models -- Small animal models for arrhythmia studies -- Use of large animal models for cardiac electrophysiology studies -- Optical mapping and calcium imaging -- Electrophysiology of single cardiomyocytes : patch clamp and other recording methods -- Invasive electroanatomical mapping and navigation -- Cardiac electrophysiological imaging : solving the inverse problem of electrocardiography -- Traditional electrophysiological mapping -- Multi-channel system for analysis of cardiac rhythmicity and conductivity in vitro -- Cardiac CT/MRI imaging for electrophysiology -- Introduction to translational research -- Clinical perspective : electrophysiology in the young and patients with congenital heart disease Summary Cardiovascular disease is the major cause of mortality and morbidity in the Western Hemisphere. While significant progress has been made in treating a major sub-category of cardiac disease, arrhythmias, significant unmet needs remain. In particular, every day, thousands of patients die because of arrhythmias in the US alone, and atrial fibrillation is the most common arrhythmia affecting millions of patients in the US alone at a given time. Therefore, there is a public need to continue to develop new and better therapies for arrhythmias. Accordingly, an ever increasing number of biomedical, ph Bibliography Includes bibliographical references and index Notes Print version record In Springer eBooks Subject Heart -- Electric properties. Electrocardiography. Heart -- Diseases -- Treatment. Electrotherapeutics. Electrophysiology. Digital computer simulation. Computer simulation. Electrophysiology Electrophysiologic Techniques, Cardiac Heart Conduction System -- physiopathology Arrhythmias, Cardiac -- physiopathology Models, Cardiovascular Computer Simulation Electrocardiography Electric Stimulation Therapy simulation. MEDICAL -- Physiology. SCIENCE -- Life Sciences -- Human Anatomy & Physiology. Heart -- Electric properties. Electrocardiography. Heart -- Diseases -- Treatment. Electrotherapeutics. Electrophysiology. Electrophysiologic Techniques, Cardiac. Heart Conduction System -- physiopathology. Arrhythmias, Cardiac -- physiopathology. Models, Cardiovascular. Computer simulation. Médecine. Electrophysiology Digital computer simulation Computer simulation Electrocardiography Electrotherapeutics Heart -- Diseases -- Treatment Heart -- Electric properties Form Electronic book Author Sigg, Daniel C. ISBN 9781441966582 1441966587 1282983016 9781282983014

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