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Title Capillary electromigration separation methods / Colin F. Poole, editor
Published Amsterdam, Netherlands : Elsevier, [2018]
©2018

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Description 1 online resource : illustrations
Series Handbooks in separation science
Handbooks in separation science
Contents Intro; Title page; Table of Contents; Copyright; Contributors; Chapter 1: Milestones in the Development of Capillary Electromigration Techniques; Abstract; 1.1 Introduction; 1.2 Instrumentation; 1.3 Electrokinetic Chromatography; 1.4 Special CE Modes; 1.5 Preconcentration in CE; 1.6 Applicability; Chapter 2: Theoretical Principles of Capillary Electromigration Methods; Abstract; 2.1 Introduction; 2.2 Theoretical Aspects of CE; 2.3 Survey of Selected CE Aspects Explored Through Theoretical Approaches; 2.4 Concluding Remarks; Chapter 3: Column Technology for Capillary Electromigration Methods
Abstract3.1 Introduction; 3.2 Dynamic Coatings; 3.3 Permanent Coatings; 3.4 Nanomaterial Layers; 3.5 Conclusions; Chapter 4: Capillary Electrophoresis in Organic Solvents; Abstract; 4.1 Preface; 4.2 Acid-Base Reactions in Organic Solvents; 4.3 Electrically Driven Migration; 4.4 Peak Broadening: Separation Efficiency, Plate Height, and Plate Number in Different Solvents; 4.5 Applications; 4.6 Conclusions; Chapter 5: Micellar and Microemulsion Electrokinetic Chromatography; Abstract; 5.1 Introduction and Terminology; 5.2 Physicochemical Background; 5.3 Separation of Neutral Solutes
5.4 Separation of Weak Electrolytes5.5 Comparison of MEKC to MEEKC; 5.6 Online Focusing; 5.7 Conclusions; Chapter 6: Capillary Gel and Sieving Electrophoresis; Abstract; Acknowledgments; 6.1 Introduction; 6.2 Gels; 6.3 Protein Analysis; 6.4 Nucleic Acid Analysis; 6.5 Miniaturization-Lab-on-a-Chip; 6.6 Conclusions; Chapter 7: Capillary Isoelectric Focusing; Abstract; 7.1 Introduction; 7.2 Resolving Power of IEF; 7.3 Capillary Wall Coating; 7.4 The Natural pH Gradient; 7.5 Focusing; 7.6 Estimation of pI; 7.7 Detection; 7.8 Conclusion; Chapter 8: Capillary Isotachophoresis; Abstract
8.1 Introduction8.2 Principles of ITP; 8.3 Apparatus; 8.4 Typical Applications of Conventional ITP; 8.5 ITP as a Preconcentration Technique for CE; 8.6 Computer Simulation; 8.7 Conclusion; Chapter 9: Capillary Electrochromatography; Abstract; Acknowledgments; 9.1 Background of Capillary Electrochromatography; 9.2 Fundamentals of CEC; 9.3 Basic Instrumentation for CEC; 9.4 Classification of CEC Columns; 9.5 Detection Methods in CEC; 9.6 Applications; 9.7 Future Trends; Chapter 10: Method Development and Validation of Capillary Electromigration Methods; Abstract; 10.1 Introduction
10.2 Analytical Quality by Design and Method Life Cycle Management10.3 Method Development; 10.4 Method Validation; 10.5 Conclusions; Chapter 11: Instrumental Platforms for Capillary and Microchip Electromigration Separation Techniques; Abstract; Acknowledgments; 11.1 Introduction; 11.2 High-Voltage Power Supplies; 11.3 Sample Injection for Conventional CE; 11.4 Temperature Control; 11.5 Detectors for Conventional CE; 11.6 CE Coupled to Flow Injection; 11.7 Chip-Based Platforms; 11.8 Sample Introduction Methods for ME; 11.9 Detection Systems for ME; 11.10 High-Throughput Analysis
Summary Capillary Electromigration Separation Methods is a thorough, encompassing reference that not only defines the concept of contemporary practice, but also demonstrates its implementation in laboratory science. Chapters are authored by recognized experts in the field, ensuring that the content reflects the latest developments in research. Thorough, comprehensive coverage makes this the ideal reference for project planning, and extensive selected referencing facilitates identification of key information. The book defines the concept of contemporary practice in capillary electromigration separation methods, also discussing its applications in small mass ions, stereoisomers, and proteins
Bibliography Includes bibliographical references and index
Notes Vendor-supplied metadata
Subject Separation (Technology)
Electrodiffusion.
SCIENCE -- Chemistry -- Industrial & Technical.
TECHNOLOGY & ENGINEERING -- Chemical & Biochemical.
Electrodiffusion
Separation (Technology)
Form Electronic book
Author Poole, Colin F., editor
ISBN 9780128096147
0128096144