Pesticides in the diets of infants and children / Committee on Pesticides in the Diets of Infants and Children, Board on Agriculture and Board on Environmental Studies and Toxicology, Commission on Life Science, National Research Council
Background and approach to the study -- Pesticide use -- Pesticide control legislation -- Approach to the study -- Special characteristics of children -- Growth -- Development -- Perinatal and pediatric toxicity -- Acute toxicity -- Neurotoxicity -- Immunotoxicity -- Carcinogenesis and mutagenesis -- Metabolism and pharmacokinetics -- Scaling and progression analysis -- Methods for toxicity testing -- Current methods: general considerations -- Acute toxicity studies -- Subchronic toxicity studies -- Chronic toxicity studies -- Developmental toxicity studies -- Reproduction studies -- Mutagenicity studies -- General metabolism studies -- Neurotoxicity studies -- Special testing -- Food and water consumption -- Food consumption surveys -- Survey methodology -- Survey design -- Sample weights -- Sample size -- Comparisons of intake data with standards -- Validation of food consumption data -- Strengths and weaknesses of the food consumption data bases in estimating pesticide exposure of children -- Water intake -- Quantification of consumption data -- Age-related differences in dietary patterns
(cont) Issues related to the evaluation of food monitoring data -- Pesticide residues -- Sources of data on usage -- Ocurrence and fate of pesticide residues -- Pesticide registration and the development of analytical methods -- Methods for sampling and analysis -- Monitoring -- Quality controls -- Limitations of the data -- Pesticides in water -- Pesticides in infant formula -- Pesticides in human milk -- Pesticides in foods -- Estimating exposures -- Use of food consumption and residue data for exposure assessment -- Long-term exposure to benomyl -- Short-term exposure to aldicarb -- Multiple exposure assessment: organophosphate insecticides -- Nondietary exposure to pesticides -- Estimating the risks -- General principles of risk assessment -- Risk assessments for infants and children