| Description |
1 online resource (xiii, 175 pages) : illustrations (some color) |
| Series |
Advances in experimental medicine and biology ; v. 608 |
|
Advances in experimental medicine and biology ; v. 608.
|
| Contents |
Overview of resistance to systemic therapy in patients with breast cancer / Ana Maria Gonzalez-Angulo, Flavia Morales-Vasquez and Gabriel N. Hortobagyi -- Roles of multidrug resistance genes in breast cancer chemoresistance / M. Tien Kuo -- Therapy-induced apoptosis in primary tumors / David J. McConkey -- Cell cycle deregulation in breast cancer: insurmountable chemoresistance or achilles' heel? / Laura Lambert and Khandan Keyomarsi -- p53, BRCA1 and breast cancer chemoresistance / Kimberly A. Scata and Wafik S. El-Deiry -- Integrin-mediated adhesion: tipping the balance between chemosensitivity and chemoresistance / Mary M. Zutter |
|
Insulin-like growth factors and breast cancer therapy / Xianke Zeng and Douglas Yee -- EGF receptor in breast cancer chemoresistance / Robert B. Dickson and T.B. Deb -- Molecular mechanisms of ErbB2-mediated breast cancer chemoresistance / Ming Tan and Dihua Yu -- Estrogen receptors in resistance to hormone therapy / Matthew H. Herynk and Suzanne A.W. Fuqua -- Novel approaches for chemosensitization of breast cancer cells: the E1A story / Yong Liao, Dihua Yu and Mien-Chie Hung |
| Summary |
Reviews critical aspects of resistance to systemic therapy in breast cancer patients. Featuring a clinical overview of the problem, this book focuses on the findings of molecular mechanisms of drug resistance. It discusses multidrug resistance by P-glycoprotein and the multidrug resistance protein family |
| Bibliography |
Includes bibliographical references and index |
| Subject |
Breast -- Cancer -- Chemotherapy
|
|
Drug resistance in cancer cells.
|
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Breast Neoplasms -- drug therapy
|
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Antineoplastic Agents -- pharmacology
|
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Drug Resistance, Neoplasm -- physiology
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Drug Resistance, Neoplasm
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Biomédecine.
|
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Sciences de la vie.
|
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Breast -- Cancer -- Chemotherapy
|
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Drug resistance in cancer cells
|
| Form |
Electronic book
|
| Author |
Yu, Dihua.
|
|
Hung, Mien-chie.
|
| LC no. |
2007030520 |
| ISBN |
9780387740379 |
|
0387740376 |
|
9780387740393 |
|
0387740392 |
|
