Emerging safety science : workshop summary / Sally Robinson, Robert Pool, and Robert Giffin [rapporteurs] ; Forum on Drug Discovery, Development, and Translation, Board on Health Sciences Policy, Institute of Medicine of the National Academies
Front Matter -- Reviewers -- Preface -- Contents -- Tables and Figures -- 1 Introduction -- 2 Investigative Toxicology: The State of the Art -- 3 Screening Technologies I: Human Cell�Based Approaches -- 4 Screening Technologies II: Toxicogenomics -- 5 Screening Technologies III: Metabolomics -- 6 Screening Technologies IV: Pharmacogenetics -- 7 Qualifying Biomarkers -- 8 Pharmacovigilance -- 9 Integration -- 10 The Future of Safety Science -- References -- Appendixes -- Appendix A: Workshop Agenda -- Appendix B: Speaker Biographies
Summary
The Institute of Medicine's Forum on Drug Discovery, Development, and Translation convened a workshop on Emerging Safety Science. A diverse group of experts from academia, industry, and government examined two broad approaches to improving drug safety: basic scientific approaches (genomics, metabolomics, pharmacogenomics, cell-based signaling, and standard toxicology) to better identify safety issues during development; and innovative techniques for collecting and analyzing postmarket data to identify safety signals more rapidly than is possible with traditional methodologies
Bibliography
Includes bibliographical references (pages 115-116)
Notes
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English
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