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E-book

Title Drugs targeting B-cells in autoimmune diseases / Xavier Bosch, Manuel Ramos-Casals, Munther A. Khamashta, editors
Published Basel : Springer, 2014

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Description 1 online resource (xi, 292 pages) : illustrations (some color)
Series Milestones in Drug Therapy, 2296-6056
Milestones in drug therapy, 2296-6056
Contents Historic Outline of the Development of Drugs Targeting B Cells / Maria J. Leandro -- Understanding B Cell Biology / Martin S. Naradikian, Jean L. Scholz, Michael A. Oropallo and Michael P. Cancro -- Pharmacological Effects and Mechanisms of Action of Agents Blocking B Cells / Ignacio Sanz -- Systemic Lupus Erythematosus: Direct B-Cell Blocking / Maria Ahijón Lana, Zozik Fattah, Susana Araujo Fernandez and David A. Isenberg -- Systemic Lupus Erythematosus: Indirect B-Cell Blocking / Pilar Brito-Zerón, Ma José Soto-Cárdenas, Soledad Retamozo and Xavier Bosch [and 2 others] -- B-Cell Targeted Therapies in Rheumatoid Arthritis / Stephan Blüml, Georg Stummvoll and Josef S. Smolen -- B-Cell Targeted Therapies in Primary Sjögren Syndrome / Pilar Brito-Zerón, Antoni Sisó-Almirall, Belchin Kostov, Xavier Bosch [and 2 others] -- Targeting B Cells in ANCA-Associated Vasculitides / Xavier Bosch and John H. Stone -- B-Cell Targeted Therapies in Systemic Sclerosis and Inflammatory Myopathies / Rohit Aggarwal, Vivek Nagaraja and Dinesh Khanna -- B-Cell Targeted Therapies in Cryoglobulinemia / Salvatore De Vita -- B-Cell Targeted Therapies in Autoimmune Cytopenias and Thrombosis / Bassem N. Matta, Rabih Nayfe, Ali T. Taher and Imad Uthman -- Targeting B Cells in Neurological Autoimmune Diseases / Maria Sepúlveda, Albert Saiz and Francesc Graus -- Targeting B Cells in Other Systemic Autoimmune Diseases / Xavier Bosch, Pilar Brito-Zerón, Munther A. Khamashta and Manuel Ramos-Casals -- Safety of B-Cell Targeted Therapies / Ian N. Bruce -- The Future Potential of Biosimilars Targeting B-Cells / Savino Sciascia, Dario Roccatello, Chary Lopez-Pedrera and Maria Jose' Cuadrado
Summary This book provides a detailed overview of B-cell directed therapies in patients with rheumatic and systemic autoimmune diseases, including rheumatoid arthritis, systemic lupus erythematosus, Sjogren syndrome, ANCA-associated vasculitis and cryoglobulinemia. Organ-specific autoimmune diseases are discussed with respect to the use of B-cell directed therapies in neurological autoimmune diseases and autoimmune cytopenias. Situations in which B-cell targeted therapy may be indicated are identified, thereby offering comprehensive support for therapeutic decisions on the basis of the latest published evidence. The book also offers a valuable reference tool for rheumatologists, internists, nephrologists, immunologists, and all specialists involved in the multidisciplinary care of patients with rheumatic and systemic autoimmune diseases
Analysis farmacologie
pharmacology
toxicologie
toxicology
biomedische wetenschappen
biomedicine
geneeskunde
medicine
immunologie
immunology
reumatiek
rheumatism
Medicine (General)
Geneeskunde (algemeen)
Notes Includes index
Bibliography Includes bibliographical references and index
Notes English
Online resource; title from PDF title page (SpringerLink, viewed November 25, 2013)
Subject Autoimmune diseases -- Chemotherapy
B cells.
Autoimmune Diseases -- drug therapy
Autoimmune Diseases -- immunology
B-Lymphocytes -- drug effects
B-Lymphocytes -- immunology
Biological Products -- therapeutic use
Immunologic Factors -- therapeutic use
B-Lymphocytes
Autoimmune diseases -- Chemotherapy
B cells
Form Electronic book
Author Bosch, Xavier, 1960- editor
Ramos-Casals, Manuel, editor
Khamashta, Munther A., editor
ISBN 9783034807067
3034807066
3034807058
9783034807050