Title Proteases in gastrointestinal tissues / edited by Uwe Lendeckel and Nigel M. Hooper

Published Dordrecht : Springer, ©2006

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Description 1 online resource (xvii, 343 pages) : illustrations Series Proteases in biology and disease ; v. 5 Proteases in biology and disease ; v. 5. Contents Protease-Activated Receptors in Gastrointestinal Function and Disease / Nigel W. Bunnett and Graeme S. Cottrell -- Matrix Metalloproteinases in Gastric Cancer / Nikhil I. Khushalani and Nithya Ramnath -- Proteases in Helicobacter pylori-Mediated Diseases / Thomas Wex, Michael Zack, and Peter Malfertheiner -- Proteases in Pancreatic Disease / Avinash Sewpaul, Jeremy J. French, and Richard M. Charnley -- PAR in the Pathogenesis of Pain in Pancreatic Disease / Pankaj J. Pasricha -- Importance of the Local Renin-Angiotensin System in Pancreatic Disease / Po Sing Leung -- Hepatitis C Viral Proteases And Inhibitors / Mingjun Huang, Avinash Phadke and Atul Agarwal -- Angiotensin Converting Enzyme in the Pathophysiology of Liver Fibrosis / Yao Hong Wei -- Matrix Metalloproteinases in Chronic Liver Disease and Liver Transplantation / Hein W. Verspaget, Johan P. Kuyvenhoven, Cornelis F.M. Sier, Bart van Hoek -- MMPs and ADAMs in Inflammatory Bowel Disease / Alicja Wiercinska-Drapalo, Jerzy Jaroszewicz, Anna Parfieniuk, Anna Moniuszko -- Chemokines and Matrix Metalloproteinases in Colorectal Cancer / Gayle G. Vaday and Stanley Zucker -- Angiotensin-Converting Enzyme (ACE) in Gut Inflammation / Fernando Magro -- Intestinal Apical Protein Transport in Health and Disease / Stephan von Hörsten, Michael Krahn, Nadine Frerker, Anja Gemeinhardt, Dennis Schwab, Silvia Slesiona, Hassan Naim, and Marwan Alfalah Summary "This book is unique for its comprehensive presentation of protease function in stomach, colon, pancreas and liver under both physiological conditions and major diseases manifesting in these four organs. The individual chapters have been written by leaders in the field who paid much attention to outline in great detail the role of proteases in the pathogenesis, diagnosis and treatment of disease. Available animal models (of disease, transgenic, or knock-out) are extensively referred to and experimental data obtained thereby are discussed in the context of patient-derived data." "Newcomers to the field and interested non-specialists will take advantage of the extensive introduction to individual proteases, protease families, and the diseases. Understanding is greatly facilitated by the clear and condensed presentation of summarised data in tables and graphs. This book is a valuable source for both clinicians and basic and clinical researchers interested in protease function and/or diseases in gastrointestinal tissues."--Jacket Analysis geneeskunde medicine volksgezondheid public health neoplasms spijsverteringsstelsel digestive system farmacologie pharmacology toxicologie toxicology biomedische wetenschappen biomedicine Medicine (General) Geneeskunde (algemeen) Bibliography Includes bibliographical references and index Notes English Print version record In Springer e-books Subject Proteolytic enzymes. Metalloproteinases. Digestive enzymes. Angiotensin converting enzyme -- Inhibitors. Digestive System Diseases -- physiopathology Peptide Hydrolases -- physiology Peptide Hydrolases Metalloproteases Digestive System Physiological Phenomena Angiotensin-Converting Enzyme Inhibitors Receptors, Proteinase-Activated Tissue Inhibitor of Metalloproteinases MEDICAL -- Gastroenterology. Metalloproteinases. Digestive enzymes. Digestive System Diseases -- physiopathology. Peptide Hydrolases -- physiology. Angiotensin-Converting Enzyme Inhibitors. Digestive System -- physiology. Receptors, Proteinase-Activated. Tissue Inhibitor of Metalloproteinases. Proteolytic enzymes. Angiotensin converting enzyme -- Inhibitors Digestive enzymes Metalloproteinases Proteolytic enzymes Form Electronic book Author Lendeckel, Uwe. Hooper, N. M. ISBN 9781402044830 1402044836 1402044828 9781402044823 1280625023 9781280625022 6610625026 9786610625024

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