Title Advances in radiation oncology in lung cancer / Branislav Jeremić, editor

Edition Third edition Published Cham, Switzerland : Springer, 2023

Click on the following:
Springer eBooks

Copies

Description 1 online resource Series Medical radiology Medical radiology (Series) Contents Intro -- Preface -- Contents -- Part I: Basic Science of Lung Cancer -- Genomic Alterations in Lung Cancer -- 1 Introduction -- 2 NSCLC -- 3 EGFR -- 4 ALK -- 5 ROS1 -- 6 BRAF -- 7 MET -- 8 RET -- 9 NTRK -- 10 HER2 -- 11 KRAS -- 12 FGFR -- 13 Small Cell Lung Cancer -- 14 Conclusion -- References -- Epigenetic Events in Lung Cancer -- 1 Introduction -- 2 Classification of the Epigenetic Modifications -- 2.1 DNA Methylation -- 2.2 Regulators of the Chromatin Structure: Histone Modifiers -- 2.2.1 Histone Acetyltransferases -- 2.2.2 Histone Deacetylases 2.2.3 Histone Methyltransferases -- 2.2.4 Histone Demethylases -- 2.3 Regulators of the Chromatin Structure: Chromatin Remodeling Complexes -- 3 Landscape of the Epigenetic Abnormalities in Lung Cancer -- 3.1 Aberrant DNA Methylation -- 3.2 Gene Abnormalities Affecting Chromatin Remodelers: The SWI/SNF Complex -- 3.3 Abnormalities in Histone Modifiers -- 4 Epigenetic-Based Therapeutic Strategies in Lung Cancer -- 4.1 DNA Methyltransferase Inhibitors -- 4.2 Histone Deacetylase Inhibitors -- 4.3 Other Epigenetic Inhibitors -- 5 Conclusions and Future Directions -- References Part II: Clinical Investigations -- Interventional Pulmonology -- 1 Introduction -- 2 Diagnostic Techniques -- 2.1 Autofluorescence Videobronchoscopy -- 2.2 Narrow-Band Imaging -- 2.3 Endobronchial Ultrasound -- 2.4 Recent Diagnostic Techniques in Interventional Pulmonology -- 3 Therapeutic Techniques -- 3.1 Techniques with Immediate Effect -- 3.1.1 Nd:YAG and Ho:YAG Laser Photoresection -- 3.1.2 Electrocautery -- 3.1.3 Argon Plasma Coagulation -- 3.2 Techniques with Delayed Effect -- References -- Pathology of Lung Cancer -- 1 Introduction -- 2 Adenocarcinoma -- 2.1 Background 2.2 Major Adenocarcinoma Patterns -- 2.3 Adenocarcinoma Variants -- 2.4 Nonmucinous Adenocarcinoma Classification -- 2.5 Grading of Lung Adenocarcinoma -- 2.6 Staging Issues Associated with Adenocarcinoma -- 3 Squamous Cell Carcinoma -- 3.1 Background -- 3.2 Histology of Squamous Cell Carcinoma -- 3.3 Differentiation of Primary Squamous Cell Carcinoma of the Lung from Metastatic Squamous Cell Carcinoma -- 4 Adenosquamous Carcinoma -- 5 Pleomorphic Carcinoma -- 6 Neuroendocrine Neoplasms of the Lung -- 6.1 Background -- 6.2 Histology of Neuroendocrine Neoplasms 6.3 Immunohistochemistry for Neuroendocrine Neoplasms -- 6.4 Ki-67 Proliferative Index for Pulmonary Neuroendocrine Neoplasms -- 7 Molecular Diagnostics in NSCLC and Triage of Limited Tissue Samples for Comprehensive Diagnosis -- 8 Pathology Assessment of Post-Neoadjuvant Resections for NSCLC -- References -- Role of Radiologic Imaging in Lung Cancer -- 1 Introduction, Technical Advances -- 2 Diagnosis of Lung Cancer/Solitary Pulmonary Nodule -- 3 T Staging/NSCLC -- 4 N Staging/NSCLC -- 5 M Staging/NSCLC -- 6 CT in Treatment Response Assessment and Follow-Up of NSCLC -- References Summary This is the third, completely updated edition of a comprehensive book in which many of the worlds leading lung cancer specialists discuss the recent advances in the radiation oncology of lung cancer and reflect on the latest research findings in lung cancer and other intrathoracic malignancies. Lung cancer remains the major cancer killer in both sexes worldwide. It is so despite significant progress in recent decades in both diagnostic and treatment approaches. New biological and technological advances in this field are now faster incorporated in the overall decision-making process and are bringing fast and substantial improvements in both survivals and quality of life of lung cancer patients. Optimized patient-oriented approaches are reality of the third decade of this millennium and thoracic oncologists strive towards nothing but seamlessly delivering it in a continuous battle with lung cancer. The first three sections of the work cover the basic science of lung cancer, clinical investigations, including histology and staging, and a wide range of fundamental treatment considerations. Current treatment strategies for small cell and non-small cell lung cancer as well as other intrathoracic malignancies are then explained and evaluated in detail, with due attention to novel approaches that promise further improvements in outcome. The various types of treatment-related toxicity are discussed, and quality of life studies and prognostic factors are also considered. After evaluating the latest technological and biological advances, including stereotactic radiotherapy, and particle therapy, the book concludes by thorough consideration of specific aspects of clinical research in lung cancer. This concise yet comprehensive book is an invaluable resource for radiation oncologists Bibliography Includes bibliographical references Notes Place and Role of PET/CT in the Diagnosis and Staging of Lung Cancer Description based on online resource; title from digital title page (viewed on October 17, 2023) Subject Lungs -- Cancer -- Radiotherapy Cancer -- Radiotherapy. Radiotherapy. Diagnostic imaging. Lung Neoplasms Radiation Oncology Radiotherapy Diagnostic Imaging Proton Therapy Positron Emission Tomography Computed Tomography Cancer -- Radiotherapy. Diagnostic imaging. Lungs -- Cancer -- Radiotherapy. Radiotherapy. Form Electronic book Author Jeremić, Branislav, editor. ISBN 9783031348471 3031348478

  Permalink