| Description |
1 online resource (xiii, 408 pages) : illustrations |
| Contents |
Basics of clinical metabolic research -- Methods for the assessment of ß-cell function in vivo -- Assessment of insulin sensitivity from steady-state and dynamic tests -- Glucose clamp techniques -- Methods of assessment of counterregulation to hypoglycaemia -- Glucose kinetics: measurement of flux rates -- Xenobiotics as probes of carbohydrate metabolism -- Tracing hepatic glucose and glycogen fluxes with ²H₂O -- Lipid kinetics -- Protein and amino acid kinetics -- Assessment of metabolic fluxes by in vivo MR spectroscopy -- Positron emission tomography in metabolic research -- Assessment of body fact content and distribution -- Tissue biopsies in diabetes research -- Assessment of vascular function -- Cardiovascular autonomic function testing -- Nerve function testing -- Kidney function -- Techniques for the investigation of the eye in diabetes -- Basics of molecular genetics: lessons from type 2 diabetes -- Good clinical practice: friend or foe? -- Statistical considerations in diabetes trials |
| Summary |
A practical "how to" guide for multiple methods in metabolism, with a critical and objective discussion of strengths, limitations, and appropriate applications of the described methods. Edited by the winner of the Oskar-Minkowski Prize of the EASD in 2006. Clinical trials in populations at risk of or with overt diabetes mellitus are being performed all around the world to test novel drugs and approaches to managing these diseases. During the last decade, new methods and techniques have been introduced and are being developed further that facilitate monitoring of metabolism and ev |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Diabetes Mellitus.
|
|
Clinical Trials as Topic.
|
|
Diabetes -- Research.
|
|
Diabetes.
|
| Form |
Electronic book
|
| Author |
Roden, Michael, Dr.
|
|
Wiley InterScience (Online service)
|
| ISBN |
0470017287 |
|
047051308X (electronic bk.) |
|
0470513098 |
|
1281031984 |
|
9780470017289 |
|
9780470513088 (electronic bk.) |
|
9780470513095 |
|
9781281031983 |
|
