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E-book

Title Diabetes & c-peptide : scientific and clinical aspects / Anders A.F. Sima, editor
Published New York : Humana Press, ©2012

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Description 1 online resource (xiii, 169 pages)
Series Contemporary diabetes
Contemporary diabetes.
Contents Preface -- Foreword -- C-peptide and Insulin -- A Happy Marriage -- Peptide Interactions of Proinsulin C-peptide -- he Effect of Combined C-peptide and Zinc on Cellular Function -- C-Peptide Signaling in the Kidney and Protection from Diabetic Nephropathy -- Role of C-Peptide in the Regulation of Microvascular Blood Flow -- Is NO-eNOS a target for C-peptide action and its protective effects on diabetic nephropathy? -- Renoprotective Effects of C-Peptide in Type I Diabetes -- The Mechanisms Underlying the Effects of C-peptide on Type I Diabetic Neuropathy -- C-peptide and Type 1 Diabetic Encephalopathy -- C-peptide: a New Molecule with Anti-Inflammatory Properties -- C-peptide: Connecting Diabetes with Macrovascular Complications -- C-peptide and Diabetic Neuropathy in Patients with Type I Diabetes -- Proatherogenic Effects of C-Peptide -- Conclusions and Future Outlook
Summary In Diabetes & C-Peptide: Scientific and Clinical Aspects, a renowned group of leading researchers and physicians offers a comprehensive overview of the role of C-Peptide in type 1 diabetes. The book is organized in five sections. An Introductory section provides the background and key features of C-peptide's physiological function and how its deficiency contributes to complications. The second section describes up-to-date information on the biochemical and molecular actions of C-peptide, including membrane binding, interactions with insulin as well as the interaction between C-peptide and zinc and effects on microvascular vasoreactivity. The third section summarizes in vivo animal studies of the type 1 diabetic complications. The fourth section reviews the clinical efforts of C-peptide on inflammation, cardiovascular complication, neuropathy and nephropathy. Finally, in the Conclusions section, a summary of the present state of C-peptide, outstanding questions, and the likely direction of the field are offered. Developed by the foremost investigators in the rapidly moving field of C-peptide research, Diabetes & C-Peptide: Scientific and Clinical Aspects is an important contribution to the literature for all researchers and physicians concerned about type 1 diabetes
Analysis Medicine
Internal medicine
Diabetes
Endocrinology
Medicine & Public Health
Bibliography Includes bibliographical references and index
Subject Diabetes.
C-peptide.
Diabetes -- Complications.
Diabetes Mellitus, Type 1 -- drug therapy
C-Peptide -- physiology
C-Peptide -- therapeutic use
Diabetes Complications -- prevention & control
C-Peptide
Diabetes Complications
HEALTH & FITNESS -- Diseases -- General.
MEDICAL -- Clinical Medicine.
MEDICAL -- Diseases.
MEDICAL -- Evidence-Based Medicine.
MEDICAL -- Internal Medicine.
Médecine.
C-peptide
Diabetes
Diabetes -- Complications
Form Electronic book
Author Sima, Anders A. F.
ISBN 9781617793912
1617793914