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Book Cover
E-book

Title Dermatotoxicology / edited by Klaus-Peter Wilhelm, Hongbo Zhai, Howard I. Maibach
Edition Eighth edition
Published London, England : Informa Healthcare, 2012
©2012

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Description 1 online resource (536 pages) : illustrations
Contents Front Cover; Contents; Contributors; Chapter 1 Pharmacogenetics and dermatology; Chapter 2 Hormesis and dermatology; Chapter 3 Toward an evidence-based dermatotoxicology; Chapter 4 How to improve skin notation; Chapter 5 Skin ion channels in health and disease; Chapter 6 Systemic toxicity; Chapter 7 Chemical respiratory allergy: Opportunities for hazard identif cation and characterization; Chapter 8 Nephrotoxicity of organic solvents from skin exposure; Chapter 9 Mechanisms in cutaneous drug hypersensitivity reactions; Chapter 10 Systemic allergic (contact) dermatitis
Chapter 11 Immunologic mechanisms in allergic and irritant contact dermatitisChapter 12 Allergic contact dermatitis: Elicitation thresholds of potent allergens in humans; Chapter 13 Photoirritation (phototoxicity, phototoxic dermatitis); Chapter 14 Contact urticaria syndrome; Chapter 15 Percutaneous penetration enhancers: An overview; Chapter 16 Chemical warfare agents; Chapter 17 Allergic contact dermatitis from ophthalmics; Chapter 18 Textiles and human skin, microclimate, cutaneous reactions: An overview
Chapter 19 Identifying the source of textile-dye allergic contact dermatitis: A guidelineChapter 20 Trichloroethylene dermatotoxicology: An update; Chapter 21 Chemical agents that cause depigmentation; Chapter 22 Hydroxychloroquine-induced retinopathy*; Chapter 23 Factors inf uencing applied amounts of topical preparations; Chapter 24 Immune reactions to copper; Chapter 25 Sodium lauryl sulfatex; Chapter 26 Water: Is it an irritant?; Chapter 27 In vivo human transfer of topical bioactive drugs among individuals: Estradiol and testosterone
Chapter 28 Pigmentation changes as a result of arsenic exposureChapter 29 Gender and pharmacokinetics*; Chapter 30 Dermatologic drug dosage in the elderly*; Chapter 31 Sensitive skin: A valid syndrome of multiple origins*; Chapter 32 Dermatotoxicology of the vulva; Chapter 33 Human scalp irritation related to arm and back*; Chapter 34 Functional map and age-related differences in human faces: Nonimmunologic contact urticaria induced by hexyl nicotinate
Chapter 35 Adhesive tape stripping reveals differences in stratum corneum cohesion between Caucasians, Blacks, and Hispanics as a function of ageChapter 36 Animal, human, and in vitro test methods for predicting skin irritation; Chapter 37 Physiologically based pharmacokinetic modeling of dermal absorption; Chapter 38 In vitro approaches to the assessment of skin irritation and phototoxicity of topically applied materials; Chapter 39 The local lymph node assay; Chapter 40 Utilization of irritation data in the local lymph node assay
Summary The foundational reference in dermal toxicology, this classic text has been completely revised to bring it up to date in the new Eighth Edition, with almost a third of its chapters being newly added. The structure of the text has also been reorganized to enable easier location of a topic of interest. With contributions from leading international experts, this continues the tradition of providing unsurpassed theoretical and practical guidance for all those working on research aspects, on practical clinical issues, and on the regulatory aspects of exposure to toxic substances. This new edition co
Bibliography Includes bibliographical references at the end of each chapters and index
Notes Online resource; title from PDF title page (ebrary, viewed, August 13, 2014)
Subject Skin -- Inflammation.
Photosensitivity disorders.
Skin absorption.
Dermatotoxicology.
Skin Diseases -- chemically induced
Photosensitivity Disorders
Dermatitis
Skin Absorption
Dermatologic Agents -- pharmacokinetics
HEALTH & FITNESS -- Diseases -- Skin.
MEDICAL -- Dermatology.
Dermatotoxicology
Photosensitivity disorders
Skin absorption
Skin -- Inflammation
Form Electronic book
Author Wilhelm, Klaus-Peter, editor
Zhai, Hongbo, editor
Maibach, Howard I., editor
ISBN 9781841848570
1841848573