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Title Dermatotoxicology methods : the laboratory worker's vade mecum / edited by Francis N. Marzulli and Howard I. Maibach
Published Boca Raton, FL : CRC Press, 2019


Description 1 online resource
Summary This work presents and evaluates methods employed to identify the potential of certain types of chemicals to adversely affect the skin. A variety of test methods are included such as tests for skin penetration, metabolism, irritation, the skin immune system, photo effects, skin cancer, and topical effects of retinoids and depigmenting chemicals. Tests for chemicals that affect the reproductive and nervous system are also included. Both animal and human tests that have been standardised and tests that are under development and employ animal alternatives are addressed in this book. Besides different testing methods, a rationale for accepting non-animal models and a review of some regulatory agency discussions about animal alternative tests are included
Bibliography Includes bibliographical references
Subject Dermatotoxicology.
Dermatotoxicology -- Toxicology
Skin absorption.
Skin Absorption
Skin Diseases -- chemically induced
Toxicity Tests -- methods
HEALTH & FITNESS -- Diseases -- General.
MEDICAL -- Clinical Medicine.
MEDICAL -- Diseases.
MEDICAL -- Evidence-Based Medicine.
MEDICAL -- Internal Medicine.
MEDICAL -- Dermatology.
MEDICAL -- Toxicology.
SCIENCE -- Life Sciences -- General.
Absorption cutanée.
Dermatotoxicologie -- Méthodologie.
Genre/Form Electronic books
Laboratory manuals.
Form Electronic book
Author Marzulli, Francis Nicholas, 1917-
Maibach, Howard I.
ISBN 0429130430