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Title CRC handbook of eicosanoids : prostaglandins and related lipids. Volume 1, Chemical and biochemical aspects. Part A / editor, Anthony L. Willis
Published Boca Raton, FL : CRC Press, 2018
Online access available from:
ProQuest Ebook Central    View Resource Record  


Description 1 online resource : illustrations
Series CRC revivals
CRC revivals
Contents Cover; Title Page; Copyright Page; TABLE OF CONTENTS; INTRODUCTION TO THE FIELD; The Eicosanoids: An Introduction and an Overview; Cyclooxygenase and Lipoxygenase Products: A Compendium; EICOSANOID PRECURSORS; The Essential Fatty Acids: Their Derivation and Role; Biosynthesis and Interconversion of the Essential Fatty Acids; Uptake and Release of Eicosanoid Precursors from Phospholipids and Other Pools: Platelets; Uptake and Release of Eicosanoid Precursors from Phospholipids and Other Lipid Pools: Lung; Phospholipases: Specificity; BIOSYNTHESIS AND METABOLISM OF EICOSANOIDS
Biosynthesis of ProstaglandinsLocalization of Enzymes Responsible for Prostaglandin Formation; Biosynthesis of Prostacyclin; Biochemistry of the Leukotrienes; Eicosanoid Transport Systems: Mechanisms, Physiological Roles, and Inhibitors; Comparative Metabolism and Fate of the Eicosanoids; Eicosanoid-Metabolizing Enzymes and Metabolites; INDEX
Summary "Building upon the extensive compilation of biochemical data featured in Volume I of the Handbook of Eicosanoids, the new Volume II describes the past, present, and potential future impact of eicosanoid research on new drug development. The reader is taken from a historical perspective through state-of-the-art basic concepts to extensive tabulation of molecular structures of compounds known to act via the eicosanoid system. Much emphasis is given to recent breakthroughs in the mechanism of action of anti-inflammatory corticosteroids and the development of receptor antagonists for prostaglandins and leukotrienes. There is also an introductory chapter that proposes areas that require further investigation and novel approaches using existing technology. This handbook will thus be invaluable for medicinal chemists, pharmacologists, and all those involved in basic research in the eicosanoid area. In addition, many parts of this handbook are suitable for use by university lecturers and students. There are 20 figures and 44 extensive tables as well as a bibliography containing more than 2,000 references that complement the text."--Provided by publisher
Bibliography Includes bibliographical references and indexes
Notes Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force. WlAbNL
Subject Arachidonic acid -- Derivatives -- Handbooks, manuals, etc
Prostaglandins -- Handbooks, manuals, etc
Arachidonic acid -- Derivatives.
MEDICAL -- Physiology.
SCIENCE -- Life Sciences -- Human Anatomy & Physiology.
Genre/Form Handbooks and manuals.
Form Electronic book
Author Willis, Anthony L., editor.
ISBN 0203712668
Other Titles Chemical and biochemical aspects. Part A
Handbook of eicosanoids