| Description |
1 online resource (xiv, 180 pages) : illustrations |
| Summary |
"The first edition focused on the classical presentations of typical and atypical dementias. We included cases of Alzheimer's disease associated with congophilic amyloid angiopathy, posterior cortical atrophy, behavioral presentation of Alzheimer's disease and mixed pathology cases between Alzheimer's and Vascular dementia. We also included Post-stroke and Vascular dementia following surgery with a Kluver Bucy syndrome. On the spectrum of frontotemporal dementia, we included cases of the behavioral variant, semantic dementia, progressive non-fluent aphasia and dementia with motor neuron disease. The first edition also included a case of Lewy body dementia and Huntington disease. Particularly regarding transmissible dementia, we included dementias cases secondary to Neurosyphilis, HIV, a Heidenhain variant of Creutzfeldt-Jakob-Disease and a Gerstmann-Straussler-Scheinker disease. Finally, the book finished with a section with dementias secondary to major depression, ethanol, and toxic encephalopathy as well as a case of adult polyglucosan body disease, a disorder characterized by a deficiency of the glycogen-branching enzyme, as well as a patient with dementia due to mitochondriopathy. This second edition incorporates advances in biomarkers and genetics. The book includes a rationale for defining typical and atypical dementia and an introduction to biomarkers for investigating atypical cases. Subsequently, a chapter provides insights regarding care planning to dementia. On the spectrum of Alzheimer's disease, we included a typical case of dementia due to Alzheimer's disease corroborated by biomarkers, a biomarker-based preclinical Alzheimer's disease, and a case of cognitive decline associated with neurofibrillary tanglepredominant dementia. As focal cortical syndromes, this edition includes cases of frontal variant due to Alzheimer's disease. There are cases of behavioral variant of frontotemporal degeneration due to C09orf75, MAPT17, progranulin, CHR3 and TARDBP mutations. The present edition also includes a case of Posterior Cortical Atrophy and an intriguing association between Posterior Cortical Atrophy with logopenia. Regarding language presentations, there are cases of Primary Progressive Apraxia of Speech as well as Agrammatic, Semantic and Logopenic presentations of Primary Progressive Aphasia. There is also an interesting case illustrating alexia without agraphia associated with Pick's disease. A number of chapters illustrate dementia syndromes with motor manifestation such as Progressive Supranuclear Palsy, Lewy body dementia,Multiple System Atrophy, Normal Pressure Hydrocephalus as well as Wilson's and Parkinson's disease. We included two cases of dementia following infarcts. Regarding prion disease, the reader will have the opportunity to contrast a Creutzfeldt-Jakob-Disease and Fatal Familial Insomnia. We added a case of paraneoplastic and a case of Hashimoto's encephalopathy for illustrating autoimmune causes of dementia. The differential diagnosis of psychiatric conditions and dementia is exemplified in a case describing a patient with bipolar disorder. The book finishes with an appendix with the updated diagnostic criteria of the typical and atypical cases presented in this second edition. We hope that this appendix would certainly streamline the learning process for students and residents. We would like to express our gratitude to all authors who contributed with cases and for their diligence and patience. We also would like to thank the suggestions received by numerous other colleagues and the incredible work of Monica Shin, MSc., who kindly volunteered to assist on the edition of this volume. Finally, we expect that the cases presented in this book would serve as an inspiration for the next generation of researchers and health professionals devoted to advance dementia care and treatments"-- Provided by publisher |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Description based on online resource; title from digital title page (viewed on February 02, 2021) |
| Subject |
Dementia -- Case studies
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Biochemical markers.
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Dementia -- diagnosis
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Diagnostic Techniques and Procedures
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Dementia -- genetics
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Biomarkers
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Biochemical markers
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Dementia
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| Genre/Form |
Case studies
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Case studies.
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Études de cas.
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| Form |
Electronic book
|
| Author |
Rosa-Neto, Pedro, editor.
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Gauthier, Serge, 1950- editor.
|
| LC no. |
2019035751 |
| ISBN |
9781316941294 |
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1316941299 |
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