| Description |
1 online resource (1 volume) : illustrations |
| Series |
Methods in molecular medicine ; 96 |
|
Methods in molecular medicine ; 96.
|
| Contents |
Studying host immune responses against duck hepatitis b virus infection / D.S. Miller [and others]-Measurement of cell-mediated immune response in woodchucks / S. Menne and P.J. Cote-Study of liver-specific expression of cytokines during woodchuck hepatitis virus infection / M. Lu and M. Roggendorf-Induction of anti-hepatitis b virus immune responses through DNA immunization / M. Geissler [and others]-Monitoring gene expression using DNA microarrays during hepatitis b virus infection / M.R. Beard and S. Locarnini-Determination of hepatitis b virus-specific cd8+ t-cell activity in the liver / M. Nascimbeni and B. Rehermann-Determining the precursor frequency of hbv nucleocapsid antigen-specific t cells / J.A. Waters and H.C. Thomas-Detection and characterization of virus-specific cd8+ t cells using the tetramer approach / X.S. He and H.B. Greenberg-In vitro analysis of hepatitis b virus specific cd4+ t cells / S. Chokshi and N.V. Naoumov-Induction of humoral and cellular immune responses to hepatitis delta virus through DNA immunization in balb/c mice / R.S. Lee [and others]-Infection of primary chimpanzee hepatocytes with recombinant hepatitis d virus particles: A surrogate model for hepatitis b virus / A. Barrera and R.E. Lanford-Study of the endocytosis and intracellular localization of subviral particles of hepatitis b virus in primary hepatocytes / D. Glebe and W.H. Gerlich-The tupaia model for the study of hepatitis b virus: Direct infection and hbv genome transduction of primary tupaia hepatocytes / F. von Weizsacker [and others]-Delivery of hepatitis b virus therapeutic agents using asialoglycoprotein receptor-based liver-specific targeting / M. Konishi, C.H. Wu and G.Y. Wu-Woodchuck hepatitis virus hepatocyte culture models / N.D. Churchill and T.I. Michalak-Duck hepatitis b virus primary hepatocyte culture model / O. Hantz and F. Zoulim-Enhancement of infection of hepg2 cells in culture by predigestion of hepadnavirus with v8 protease / X. Lu and T.M. Block-Construction of recombinant adenoviruses that produce infectious hepatitis b virus / M. Sprinzl, J. Dumortier and U. Protzer-Baculovirus-mediated gene transfer for the study of hepatitis b virus / H.C. Isom [and others]-Transgenic hepatitis b virus mouse model in the study of chemotherapy / J.D. Morrey-Transplantation of human hepatocytes in immunodeficient upa mice: A model for the study of hepatitis b virus / J. Petersen [and others]-Duck hepatitis b virus model in the study of hepatitis b virus / L. Cova and F. Zoulim-Hepatitis b virus transgenic severe combined immunodeficient mouse model of acute and chronic liver disease / M.A. Feitelson, J.D. Larkin and R.F. Schinazi-The chimpanzee model: Contributions and considerations for studies of hepatitis b virus / P. Gagneux and E.A. Muchmore-Hepatitis b in liver transplant recipients as a special model of antiviral drug development / R.G. Gish and A. Wakil-Hepatitis delta virus transfection for the mouse in vivo model / J. Chang, A. Lerro and J.M. Taylor-Hepatitis delta virus rna transfection for the cell culture model / T.B. Macnaughton and M.M. Lai-Analysis of hepatitis b virus dynamics and its impact on antiviral development / M. Tsiang and C.S. Gibbs-Genotyping anti-hepatitis b virus drug resistance / E.J. Bourne [and others]-A parsimonious method for screening drug combinations for antihepadnaviral activity using a parametric dose-response surface approach / T. Shaw and S. Locarnini-Hepatitis b virus: Where are we and where are we going? / M.P. Manns, J. Hadem and H. Wedemeyer-Designing studies to evaluate anti-hepatitis b virus therapies: From the perspective of studies for the registration of pharmaceutical products / A.B. Murray-Specific considerations in the design of hepatitis b virus clinical studies in the far east / M.F. Yuen and C.L. Lai-Studying the treatment of chronic hepatitis b viral infection in special populations / R.G. Gish and S. Locarnini-Designing clinical development programs for anti-hepatitis b virus drugs / N.A. Brown-Testing antivirals against hepatitis delta virus: Farnesyl transferase inhibitors / B.B. Bordier and J.S. Glenn |
| Summary |
Despite the availability of an effective vaccine, there are still 400 million people worldwide who are chronically infected with the hepatitis B and D viruses (HBV and HDV), and more work still needs to be done in all of the key areas of managing the disease. In Hepatitis B and D Protocols, leading investigators and clinicians have joined forces to create a broad-ranging collection of cutting-edge techniques for the study of HBV and HDV infections and for the development of therapies to treat them. In this second of two volumes, Immunology, Model Systems, and Clinical Studies, the authors focus on protocols for the study of host immune responses to infection, in vitro and in vivo models of infection, and the development of antivirals. Each fully tested protocol is described in step-by-step detail by an established expert in the field and includes a background introduction outlining the principle underlying the technique, equipment and reagent lists, and tips on troubleshooting and avoiding known pitfalls. An accompanying first volume, Detection, Genotypes, and Characterization, contains user-friendly protocols for the identification and quantification of viral markers, the detection and impact of viral variants, and the study of the viral life cycle. Taken together, Hepatitis B and D Protocols, Volume 1: Detection, Genotypes, and Characterization and Volume 2: Immunology, Model Systems, and Clinical Studies offer both new and experienced investigators an encyclopedic collection of powerful tools for studying HBV and HDV infections, as well as an essential resource for finding new therapies to treat chronically infected patients |
| Analysis |
hepatitis |
|
hepatitis d |
|
immunologie |
|
immunology |
|
hepatitis delta virus |
|
immuniteitsreactie |
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immune response |
|
hepatitis b |
|
biologische technieken |
|
biological techniques |
|
hepatitis b virus |
|
virusziekten |
|
viral diseases |
|
virale hepatitis |
|
viral hepatitis |
|
rna viruses |
|
protocollen |
|
protocols |
|
Virology |
|
Virologie |
| Bibliography |
Includes bibliographical references and indexes |
| Notes |
English |
|
Print version record |
| In |
Springer Protocols |
| Subject |
Hepatitis B -- Laboratory manuals
|
|
Hepatitis B virus -- Laboratory manuals
|
|
Delta-associated agent -- Laboratory manuals
|
|
Delta infection -- Laboratory manuals
|
|
Hepatitis B.
|
|
Delta infection.
|
|
Hepatitis B
|
|
Hepatitis D
|
|
MEDICAL -- Hepatology.
|
|
Delta-associated agent
|
|
Delta infection
|
|
Hepatitis B
|
|
Hepatitis B virus
|
| Genre/Form |
Laboratory manuals
|
|
Laboratory manuals.
|
|
Manuels de laboratoire.
|
| Form |
Electronic book
|
| Author |
Hamatake, Robert Kiyoshi, 1953-
|
|
Lau, Johnson Y. N. (Johnson Yiu-Nam)
|
| ISBN |
9781592596706 |
|
1592596703 |
|
9781588291080 |
|
1588291081 |
|
