| Description |
1 online resource (xvii, 660 pages) : illustrations (some color) |
| Contents |
Overview and history of DNA typing -- DNA biology review -- Sample collection, DNA extraction and DNA quantitation -- The polymerase chain reaction (DNA amplification) -- Commonly used short tandem repeat markers and commercial kits -- Biology of STRs : stutter products, non-template addition, microvariants, null alleles, and mutation rates -- Forensic issues : degraded DNA, PCR inhibition, contamination, mixed samples and low copy number -- Single nucleotide polymorphisms and other bi-allelic markers -- Y chromosome DNA testing -- Mitochondrial DNA analysis -- Non-human DNA testing and microbial forensics -- DNA separation methods : slab-gel and capillary electrophoresis -- DNA detection methods : fluorescent dyes and silver-staining -- Instrumentation for STR typing : ABI 310, ABI 3100, FMBIO systems -- STR genotyping issues -- Laboratory validation -- New technologies, automation, and expert systems -- Combined DNA index system (CODIS) and the use of DNA databases -- Basic genetic principles, statistics, and probability -- STR population database analyses -- Profile frequency estimates, likelihood ratios, and source attribution -- Approaches to statistical analysis of mixtures and degraded DNA -- Kinship and parentage testing -- Mass disaster DNA victim identification |
| Summary |
This enormously successful book gains ten new chapters providing valuable insight on this fascinating new technology! |
| Bibliography |
Includes bibliographical references and indexes |
| Notes |
Print version record |
| Subject |
DNA fingerprinting.
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Forensic genetics.
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DNA -- Synthesis.
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Information storage and retrieval systems -- Nucleotide sequence.
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Medical jurisprudence.
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DNA Fingerprinting -- methods
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Databases, Nucleic Acid
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Forensic Medicine
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DNA Fingerprinting
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forensic medicine.
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SCIENCE -- Life Sciences -- Genetics & Genomics.
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Medical jurisprudence
|
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Information storage and retrieval systems -- Nucleotide sequence
|
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DNA fingerprinting
|
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DNA -- Synthesis
|
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Forensic genetics
|
|
Genética.
|
| Form |
Electronic book
|
| ISBN |
9780080470610 |
|
0080470610 |
|
9780121479527 |
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0121479528 |
|
