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Book Cover
E-book
Author Holmes, Frederic Lawrence.

Title Meselson, Stahl, and the replication of DNA : a history of "the most beautiful experiment in biology" / Frederic Lawrence Holmes
Published New Haven, CT : Yale University Press, 2001

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Description 1 online resource (xii, 503 pages) : illustrations
Contents Contents -- Preface -- Acknowledgments -- Introduction -- The Replication Problem -- Meselson and Stahl -- Twists and Turns -- Crossing Fields: Chemical Bonds to Biological Mutants -- Dense Solutions -- The Big Machine -- Working at High Speed -- The Unseen Band -- One Discovery, Three Stories -- An Extremely Beautiful Experiment -- Centrifugal Forces -- The Subunits of Semiconservative Replication -- Images of an Experiment -- Afterword -- Abbreviations Used in Notes -- Notes -- Index
Summary In 1957 Matthew Meselson and Frank Stahl produced a landmark experiment confirming that DNA replicates as predicted by the double helix structure Watson and Crick had recently proposed. It also gained immediate renown as a 'most beautiful' experiment whose beauty was tied to its simplicity. This book vividly reconstructs the complex route that led to the Meselson-Stahl experiment and provides an inside view of day-to-day scientific research - its unpredictability, excitement, intellectual challenge, and serendipitous windfalls, as well as its frustrations, unexpected diversions away from original plans, and chronic uncertainty
Bibliography Includes bibliographical references (pages 449-496) and index
Notes Print version record
Subject Meselson, Matthew.
Stahl, Franklin W.
SUBJECT Meselson, Matthew fast
Stahl, Franklin W. fast
Meselson, Matthew Stanley 1930- gnd
Stahl, Franklin William 1929- gnd
Meselson, Matthew Stanley. swd
Stahl, Franklin William. swd
Subject DNA replication -- Experiments -- History
Molecular biology -- Experiments -- History
DNA replication.
DNA Replication
Molecular Biology -- history
SCIENCE -- Life Sciences -- Genetics & Genomics.
SCIENCE -- History.
DNA replication
Molecular biology -- Experiments
Replikation
Meselson-Stahl-Experiment
DNA.
Replicatie (biochemie)
Genre/Form History
Form Electronic book
ISBN 9780300129663
0300129661
1281730459
9781281730459