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Title Cancer cytogenetics : methods and protocols / by Lynda J. Campbell
Edition 2nd ed
Published New York, N.Y. : Humana Press, ©2011


Description 1 online resource (x, 272 pages) : illustrations (some color)
Series Springer protocols
Methods in molecular biology, 1940-6029 ; 730
Springer protocols (Series)
Methods in molecular biology (Clifton, N.J.) ; v. 730
Contents Introduction / Lynda J. Cambell -- Evolution of cytogenetic methods in the study of cancer / Lynda J. Campbell -- Fluorescence in situ hybridization methods and troubleshooting applied to fixed cell suspensions / John Swansbury, Toon Min, and Shilani Aruliah -- Chronic myeloid leukemia : cytogenetic methods chronic myeloid leukemia : cytogenetic methods / Christine M. Morris -- Cytogenetic analysis in acute myeloid leukaemia / Lynda J. Campbell and Joanne S. White -- Cytogenetics in myelodysplastic syndromes / Kazuma Ohyashiki, Atsushi Kodama, and Junko H. Ohyashiki -- Cytogenetics of myeloproliferative neoplasms / Lynda J. Campbell -- Acute lymphoblastic leukaemia / Claire Schwab and Christine J. Harrison -- Cytogenetic methods in chronic lymphocytic leukemia / Claudia Haferlach and Ulrike Bacher -- Genetic abnormalities in non-hodgkin's lymphoma as revealed by conventional and molecular cytogenetics methods of analyses / Suresh C. Jhanwar and Ryan C. Denley -- Metaphase cytogenetic techniques in multiple myeloma / Jeffrey R. Sawyer -- Detection of chromosome abnormalities using cytoplasmic immunoglobulin staining and FISH in myeloma / Bruce R. Mercer and Kathleen C. Rayeroux -- Cytogenetics of solid tumours / Robyn Lukeis and Mary Suter -- Fluorescence in situ hybridization on formalin-fixed, paraffin-embedded tissue sections / Adrian Zordan -- Use of M-FISH and M-BAND to define chromosome abnormalities / Ruth N. MacKinnon and Ilse Chudoba -- Utility of array comparative genomic hybridization in cytogenetic analysis / Rashmi R. Singh, K-John J. Cheung, and Douglas E. Horsman -- Single nucleotide polymorphism microarray analysis of genetic alterations in cancer / Charles G. Mullighan -- Cytogenetic analysis and reporting / Lynda J. Campbell
Summary [Publisher-supplied data] Cytogenetic studies of malignancy have become an essential tool in the clinical management of cancer patients. Cancer Cytogenetics: Methods and Protocols presents eminently practical key cytogenetic and FISH techniques for every stage of diagnostic service. Experts in the field describe detailed cytogenetic analysis methods, fluorescence in situ hybridization and array methods currently being applied to investigate and diagnose different varieties of cancer. Written in the highly successful Methods in Molecular Biology series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, and step-by-step, readily reproducible laboratory protocols. The authors of the various chapters have also provided extensive notes to guide individuals who are new to these methods through the pitfalls that bedevil all such testing. Authoritative and accessible, Cancer Cytogenetics: Methods and Protocols serves as an ideal guide to scientists of all backgrounds, allowing them to either establish new techniques in their laboratories or find the different variations of standard methods helpful in improving their results
Analysis neoplasms
biomedische wetenschappen
Medicine (General)
Geneeskunde (algemeen)
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Cancer -- Genetic aspects -- Laboratory manuals
Cytogenetics -- methods
Neoplasms -- genetics
Cancer -- Genetic aspects
Genre/Form Laboratory manuals
Laboratory manuals.
Manuels de laboratoire.
Form Electronic book
Author Campbell, Lynda J.
ISBN 9781617790744