Book Cover; Half-Title; Title; Copyright; Contents; Acknowledgements; Abbreviations; Chemical Abbreviations; Foreword; Preface; Captions for Colour Plates in Chapter 6; 1 Introduction; 2 Evolution of the P450 Superfamily; 3 The P450 Catalytic Cycle and Oxygenation Mechanism; 4 P450 Substrate Specificity and Metabolism; 5 Induction, Regulation and Inhibition; 6 Structural Models of P450s and Related Topics; Bibliography; References; Index
Summary
This guide to the structure, function and mechanism of the cytochromes P450 focuses on the role of P450s in xenobiotic metabolism and toxicity. Colour illustrations show how modelling of P450s can rationalize their substrate specificity for the metabolism of both endogenous and exogenous chemicals
Analysis
Enzymes
Bibliography
Includes bibliographical references (page 293) and index
