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Title Cytochrome P450 / edited by Michael R. Waterman, Eric F. Johnson
Published San Diego : Academic Press, [1991]


Location Call no. Vol. Availability
 W'PONDS  616.0756 Met/Mie  206  AVAILABLE
Description xxxvii, 716 pages : illustrations
Series Methods in enzymology ; v. 206
Methods in enzymology ; v. 206
Contents P450 gene nomenclature based on evolution / Daniel W. Nebert [and others] -- Modeling of mammalian P450s on basis of P450cam x-ray structure / Thomas L. Poulos, Michael R. Waterman and Eric F. Johnson -- Mutagenesis of cytochromes P450cam and b5 / Stephen G. Sligar [and others] -- Chemical modification of interaction between adrenodoxin and cytochrome P450scc / Francis S. Millett [and others] -- Azidowarfarin as photoaffinity probe of cytochromes P450 / Laurence S. Kaminsky [and others] -- Cell-free analysis of targeting of cytochrome P450 to microsomal membranes / Elzbieta Szczesna-Skorupa [and others] -- Biosynthesis and intracellular sorting of mitochondrial forms of cytochrome P450 / Tsuneo Omura [and others] -- Expression of mammalian cytochrome P450 using vaccinia virus / Frank J. Gonzalez [and others] -- Expression of mammalian cytochrome P450 using baculovirus / Frank J. Gonzalez [and others] -- Heterologous expression of mammalian P450 in COS cells / Barbara J. Clark [and others] -- Expression of mammalian P450s in Escherichia coli / Todd D. Porter [and others] -- V79 Chinese hamster cells genetically engineered for stable expression of cytochromes P450 / Johannes Doehmer [and others] -- Expression of cytochrome P450 cDNAs in human B lymphoblastoid cells: Applications to toxicology and metabolite analysis / Charles L. Crespi, Michael R. Waterman and Eric F. Johnson -- Expression of mammalian cytochrome P450 enzymes using yeast-based vectors / F. Peter Guengerich [and others] -- Genetic analysis of cytochrome P450 system / Nigel K. Spurr [and others] -- Functional analysis of mutant P450(C21) genes in COS cell expression system / Yujiro Higashi [and others] -- Genetic polymorphism of debrisoquine oxidation: restriction fragment analysis and allele-specific amplification of mutant alleles of CYP2D6 / Markus H. Heim [and others] -- Characterization of human P450IIC isozymes by using yeast expression system / Ryuichi Kato [and others] -- Production of site-specific P450 antibodies using recombinant fusion proteins as antigens / Thomas Friedberg [and others] -- Immunoisolation of human microsomal cytochromes P450 using autoantibodies / Ulrich M. Zanger, Michael R. Waterman and Eric F. Johnson -- Identification of human cytochrome P450s as autoantigens / Michael P. Manns [and others]
Antipeptide antibodies in studies of cytochromes P450IA / Robert J. Edwards [and others] -- Production and purification of antibodies against rat liver P450 enzymes / Andrew Parkinson [and others] -- Rat hepatic P450IIA and P450IIC subfamily expression using catalytic, immunochemical, and molecular probes / David J. Waxman, Michael R. Waterman and Eric F. Johnson -- Expression of genes within mouse IIA and IID subfamilies: Simultaneous measurement of homologous P450 mRNAs / Masahiko Negishi [and others] -- CYP4A subfamily: Functional analysis by immunohistochemistry and in Situ hybridization / James P. Hardwick, Michael R. Waterman and Eric F. Johnson -- Quantitation of related gene products by nuclear run-on and northern blot analysis / Robert H. Tukey [and others] -- Isolating cytochrome P450 cDNA and genomic clones: Library screening with synthetic DNA oligomers / Christopher Hassett [and others] -- P450 Phosphorylation in isolated hepatocytes and in Vivo / John A. Koch [and others] -- Cytochrome P450 turnover / Maria Almira Correia, Michael R. Waterman and Eric F. Johnson -- Induction of diabetes and evaluation of diabetic state on P450 expression / John B. Schenkman, Michael R. Waterman and Eric F. Johnson -- Hepatocyte culture in study of P450 regulation / Donna Li [and others] -- Induction protocols for cytochromes P450IIIA in Vivo and in primary cultures of animal and human hepatocytes / Martine Daujat [and others] -- Induction protocols for the cytochrome P450IVA subfamily in animals and primary hepatocyte cultures / G. Gordon Gibson [and others] -- Cytochrome P450 expression and metabolism in isolated rabbit renal epithelium / Dennis R. Koop [and others] -- Culturing steroidogenic cells / Peter J. Hornsby [and others] -- Selections for and against cells possessing cytochrome P450IA1-dependent aryl hydrocarbon hydroxylase activity / Oliver Hankinson, Michael R. Waterman and Eric F. Johnson -- Use of gel retardation to analyze protein-DNA interactions upstream of CYPIA1 gene / Emily S. Shen [and others] -- Xenobiotic responsive elements controlling inducible expression by planar aromatic compounds and phenolic antioxidants / Thomas H. Rushmore [and others] -- Induction of cytochromes P450IA1 and P450IA2 and measurement of catalytic activities / A.D. Rodrigues [and others] -- [omega]- and ([omega]-1)-hydroxylation of eicosanoids and fatty acids by high-performance liquid chromatography / Richard T. Okita [and others] -- Cytochrome P450 arachidonic acid epoxygenase: Stereochemical characterization of epoxyeicosatrienoic acids / Jorge H. Capdevila [and others]
Measurement of steroid hydroxylation reactions by high-performance liquid chromatography as indicator of P450 identity and function / Michael P. Arlotto [and others] -- P450-catalyzed steroid hydroxylation: Assay and product identification by thin-layer chromatography / David J. Waxman, Michael R. Waterman and Eric F. Johnson -- Assay of aromatase activity / Edwin D. Lephart [and others] -- Reversed-phase high-performance liquid chromatography assay of cholesterol 7[alpha]-hydroxylase / John Y.L. Chiang, Michael R. Waterman and Eric F. Johnson -- Induction, inhibition, and analysis of vitamin D metabolism in cultured cells / Joseph L. Napoli [and others] -- Measurement of cytochrome P450 activation of xenobiotics using the ames Salmonella test / M.E. McManus [and others] -- Bufuralol, dextromethorphan, and debrisoquine as prototype substrates for human P450IID6 / Thomas Kronbach, Michael R. Waterman and Eric F. Johnson -- Breath tests as noninvasive assays of P450s / Paul B. Watkins, Michael R. Waterman and Eric F. Johnson -- Site of action of substrates requiring cytochrome b5 for oxidation by cytochrome P450 / Lucy A. Waskell [and others] -- Mechanism-based inactivation of cytochrome P450: Isolation and characterization of N-alkyl heme adducts / Paul R. Ortiz de Montellano, Michael R. Waterman and Eric F. Johnson -- Dihalomethyl compounds as mechanism-based inactivators of cytochromes P450 / James R. Halpert [and others] -- Active site-directed inhibitors of steroid hydroxylase cytochromes P450 / Larry E. Vickery, Michael R. Waterman and Eric F. Johnson -- Cytochrome P450 metabolic intermediate complexes from macrolide antibiotics and related compounds / Michael R. Franklin, Michael R. Waterman and Eric F. Johnson -- Isolation of P450 enzymes from human liver / Judy L. Raucy [and others] -- Constitutive and inducible forms of cytochrome P450 from hepatic mitochondria / Rass M. Shayiq [and others] -- Induction, purification, and characterization of cytochrome P450IIE / Chung S. Yang [and others] -- Purification and characterization of cytochromes P450 in rabbit nasal microsomes / Xinxin Ding [and others] -- Bacterial cytochromes P450: Isolation and identification / Julian A. Peterson [and others] -- Characterization of cytochrome P450 in extrahepatic tissues / Richard M. Philpot, Michael R. Waterman and Eric F. Johnson -- Identification and localization of cytochromes P450 expressed in brain / Margaret Warner [and others] -- Identification of cytochrome P450 in extrahepatic tissues by cross-hybridization of oligonucleotides and cDNAs / Maria Strömstedt [and others] -- Identification and localization of cytochromes P450 in gut / Henry W. Strobel [and others]
Analysis Enzymology
Cellular biology
Molecular biology
Bibliography Includes bibliographical references and indexes
Subject Cytochrome P-450.
Cytochrome P-450 Enzyme System.
Author Waterman, Michael R.
Johnson, Eric F.
LC no. 54009110
ISBN 9780121821074 (alk. paper)
0121821072 (alk. paper)