Title Biophysics of computation : information processing in single neurons / Christof Koch

Published New York : Oxford University Press, 1999

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Description 1 online resource (xxiii, 562 pages) : illustrations Series Computational neuroscience Computational neuroscience. Contents The membrane equation --Linear cable theory -- Passive dendritic trees -- Synaptic input -- Synaptic interactions in a passive dendritic tree -- The Hodgkin-Huxley model of action potential generation -- Phase space analysis of neuronal excitability -- Ionic channels -- Beyond Hodgkin and Huxley: calcium and calcium-dependent potassium currents -- Linearizing voltage-dependent currents -- Diffusion, buffering and binding -- Dendritic spines -- Synaptic plasticity -- Simplified models of individual neurons -- Stochastic models of single cells -- Bursting cells -- Input resistance, time constants, and spike initiation -- Synaptic input to a passive tree -- Voltage-dependent events in the dendritic tree -- Unconventional computing -- Computing with neurons: a summary -- Appendix A: Passive membrane parameters -- Appendix B: A miniprimer on linear systems analysis -- Appendix C: Sparce matrix methods for modeling single neurons Summary Neural network research often builds on the fiction that neurons are simple linear threshold units, completely neglecting the highly dynamic and complex nature of synapses, dendrites, and voltage-dependent ionic currents. Biophysics of Computation: Information Processing in Single Neurons challenges this notion, using richly detailed experimental and theoretical findings from cellular biophysics to explain the repertoire of computational functions available to single neurons. The author shows how individual nerve cells can multiply, integrate, or delay synaptic inputs and how information can b Bibliography Includes bibliographical references (pages 503-552) and index Notes English Print version record Subject Computational neuroscience. Neurons. Neural networks (Neurobiology) Action potentials (Electrophysiology) Neural conduction. Neural circuitry. Neurons Action Potentials Nerve Net Neural Conduction SOCIAL SCIENCE -- Anthropology -- Physical. Neural circuitry Action potentials (Electrophysiology) Computational neuroscience Neural conduction Neural networks (Neurobiology) Neurons Neurologie Aktionspotenzial Neuronales Netz Nervennetz Signaltransduktion Konnektionismus Biophysik Datenverarbeitung Nervenzelle Informationsverarbeitung Neurobiologie. Actiepotentialen. Neurotransmissie. Neurones. Réseaux neuronaux (physiologie) Conduction nerveuse. Form Electronic book LC no. 97051390 ISBN 9780199760558 0199760551 1280595094 9781280595097 9786613624925 6613624926 0197562337 9780197562338

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