Colorectal Cancer: Epidemiology; Mouse Models of Intestinal Cancer; The Chromosomal-Instability Pathway and APC Gene Mutation in Colorectal Cancer; DNA Methylation in Colorectal Cancer: Multiple Facets of Tumorigenesis; Pathways and Pathology; Familial Adenomatous Polyposis; DNA Mismatch Repair and Lynch Syndrome; MUTYH -Associated Polyposis; Familial Colorectal Cancer Type X; Families with Serrated Neoplasia of the Colon; Peutz-Jeghers Syndrome; Juvenile Polyposis; BLM Mutation and Colorectal Cancer Susceptibility; The Role of p53 in Colorectal Cancer
Summary
Genetic susceptibility refers to how variations in a person's genes increase or decrease his or her susceptibility to environmental factors, such as chemicals, radiation and lifestyle (diet and smoking). This book explores various findings in the area of genetic susceptibility to gastrointestinal cancers, focusing on molecular epidemiology