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Book Cover
Author Garland, John M. author

Title Colony-stimulating factors : molecular & cellular biology / edited by John M. Garland, Peter J. Quesenberry, Douglas J. Hilton
Edition Second edition
Published Boca Raton : CRC Press, 2020


Description 1 online resource
Contents Overview: introduction to the haematopoietic system; surrogate assays for haematopoietic stem cell activity; receptors for haematopoietic regulators; regulation of the cell cycle by kinases and cyclins; gene organization and regulation; cytokines and apoptosis -- the mechanism of regulation of cell death; haematopoietic microenvironments; extracellular matrix- and membrane-bound cytokines; transfection of stem cells and gene therapy. Colony-stimulating factor: granulocyte-macrophage colony-stimulating factor and its receptor; granulocyte colony-stimulating factor; human interleukin-3 -- an overview; macrophage colony-stimulating factor; erythropoietic; the role of interleukin-4 in normal and malignant human haematopoietic effects of interleukin-1; kit-ligand-stem cell factor; interleukin-5. Cytokines: macrophages inflammatory protein-1 alpha; transforming growth factor-beta, tumour necrosis factor-alpha, and macrophage inflammatory protein-1 alpha are bidirectional regulators of haematopoietic cell growth; leukaemia inhibitory factor; interleukin-12 in haematopoiesis; ex vivo expansion of haematopoietic stem and progenitor cells; clinical use of cytokines
Notes Previously issued in print: 2019
Description based on CIP data; resource not viewed
Subject Colony-stimulating factors (Physiology)
Colony-Stimulating Factors
Colony-stimulating factors (Physiology)
Form Electronic book
Author Garland, John M., 1942- editor.
Quesenberry, Peter J., editor
Hilton, Douglas J. (Douglas James), 1964- editor.
ISBN 9781000148459