Title Bayesian adaptive design for immunotherapy and targeted therapy / Haitao Pan, Ying Yuan

Published Singapore : Springer, [2023] ©2023

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Description 1 online resource (xi, 262 pages) : illustrations (some color) Contents Introduction to Adaptive Design and Delayed Outcomes -- Basics of Bayesian Statistics -- Phase I Dose-finding Design -- Phase II Design for Interim Monitoring -- Phase I-II Dose-finding Design -- Drug Combination Trial Design -- Conclusion Summary This book provides a comprehensive review of novel adaptive trial designs for targeted therapies and immunotherapies. This book covers a wide range of novel statistical designs for various clinical settings, including early phase dose-escalation study, proof-of-concept trials, and confirmatory studies with registrational. The book includes real-life examples and software to facilitate practitioners to learn and use the designs in practice Bibliography Includes bibliographical references Notes Print version record Subject Immunotherapy -- Statistical methods Drug targeting -- Statistical methods Clinical trials -- Design -- Statistical methods Bayesian statistical decision theory. Biometry. Clinical Trial Protocols as Topic Adaptive Clinical Trials as Topic Biostatistics Biometry Bayes Theorem biometrics. Bayesian statistical decision theory Form Electronic book Author Yuan, Ying, author ISBN 9789811981760 9811981760

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