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Book Cover
E-book
Author Powell, Lynda H., author

Title Behavioral clinical trials for chronic diseases : scientific foundations / Lynda H. Powell, Kenneth E. Freedland, Peter G. Kaufmann
Published Cham : Springer, 2021

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Description 1 online resource (1 volume) : illustrations (black and white, and color)
Contents Introduction: the window of opportunity -- A selected history of randomized behavioral clinical trials: what we learned -- A clinically significant problem and a clincially significant benefit -- The process of developing a behavioral treatment for chronic disease -- The hypothesized pathway from behavioral treatment to chronic disease -- Equipoise, blinding, and investigator discipline -- Sensitivity to diversity -- Protection of randomization -- Choice of appropriate control group -- Readiness to conduct a behavioral randomized clinical trial -- Concluding remarks
Summary This is the first comprehensive guide to the design of behavioral randomized clinical trials (RCT) for chronic diseases. It includes the scientific foundations for behavioral trial methods, problems that have been encountered in past behavioral trials, advances in design that have evolved, and promising trends and opportunities for the future. The value of this book lies in its potential to foster an ability to speak the language of medicine through the conduct of high-quality behavioral clinical trials that match the rigor commonly seen in double-blind drug trials. It is relevant for testing any treatment aimed at improving a behavioral, social, psychosocial, environmental, or policy-level risk factor for a chronic disease including, for example, obesity, sedentary behavior, adherence to treatment, psychosocial stress, food deserts, and fragmented care. Outcomes of interest are those that are of clinical significance in the treatment of chronic diseases, including standard risk factors such as cholesterol, blood pressure, and glucose, and clinical outcomes such as hospitalizations, functional limitations, excess morbidity, quality of life, and mortality. This link between behavior and chronic disease requires innovative clinical trial methods not only from the behavioral sciences but also from medicine, epidemiology, and biostatistics. This integration does not exist in any current book, or in any training program, in either the behavioral sciences or medicine
Notes Print version record
Subject Chronic diseases -- Treatment -- Research
Behavior therapy -- Research
Chronic Disease -- therapy
Behavior Therapy
Behavior therapy -- Research
Malalties cròniques.
Teràpia de la conducta.
Investigació mèdica.
Assaigs clínics.
Genre/Form Electronic books
Llibres electrònics.
Form Electronic book
Author Freedland, Kenneth E., author
Kaufmann, Peter G., author
ISBN 9783030393304
3030393305