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Title Ischemic stroke : from basic mechanisms to new drug development / volume editor, Chung Y. Hsu
Published Basel ; New York : Karger, ©1998


Description 1 online resource (ix, 166 pages) : illustrations
Series Monographs in clinical neuroscience ; vol. 16
Monographs in clinical neuroscience ; vol. 16.
Summary Stroke is the third leading cause of death in industrialized countries and the number one cause of disability in adults. Ischemic strokes constitute approximately 80% of all strokes, and until recently, no effective therapies had been available. The successful tissue plasminogen activator (tPA) trials open a new era of stroke management with a proven therapeutic now available to patients if they arrive at the hospital within hours of the onset of symptoms. Recent advances in our understanding of the molecular mechanisms of ischemic brain injury and vascular pathology have opened up new avenues for the development of novel therapeutic strategies. The premise that substantial reduction of brain damage after ischemic stroke by therapeutic intervention has now been confirmed in animal stroke models, sets a realistic goal for future treatment of stroke patients. This book covers topics ranging from fundamental molecular mechanisms of ischemic brain injury to the most current views on the clinical stroke trials and academic and industrial efforts to develop new drugs. The authors are leading authorities in their own fields in basic and clinical stroke research. As a timely and comprehensive volume, it will be of immense value to basic and clinical investigators, neurologists and neurosurgeons who manage stroke patients, neuroscientists interested in various aspects of brain injury, and researchers in the pharmaceutical industry who are engaged in new drug development
Analysis cerebral ischaemia
Bibliography Includes bibliographical references and indexes
Notes Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. MiAaHDL
Print version record
digitized 2010 HathiTrust Digital Library committed to preserve pda MiAaHDL
Subject Cerebral ischemia.
Cerebral ischemia -- Chemotherapy
Brain Ischemia -- physiopathology
Brain Ischemia
Brain Ischemia -- drug therapy
Cerebral ischemia
Cerebral ischemia -- Chemotherapy
Form Electronic book
Author Hsu, Chung Y
ISBN 9783318002553