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Book Cover
E-book
Author Smith, Bradley D

Title Synthetic Receptors for Biomolecules : Design Principles and Applications
Published Cambridge : Royal Society of Chemistry, 2015

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Description 1 online resource (467 pages)
Series Monographs in Supramolecular Chemistry
Monographs in supramolecular chemistry.
Contents 880-01 Cover; Contents; Preface; Chapter 1 Applications of Synthetic Receptors for Biomolecules; 1.1 Biomolecule Recognition; 1.2 Types of Synthetic Receptors; 1.2.1 Small Organic Molecules; 1.2.2 Inorganic Molecules; 1.2.3 Synthetic Oligomers; 1.2.4 Molecular Imprinted Polymers; 1.2.5 Dendrimers; 1.2.6 Nanoparticles; 1.3 Common Applications; 1.3.1 Separations; 1.3.2 Imaging and Sensing; 1.3.3 Catalysis; 1.3.4 Pharmaceutical Activity; 1.4 Future Directions; 1.4.1 Logic Devices; 1.4.2 Biomolecule Responsive Materials; 1.4.3 Drug Delivery; 1.4.4 Biomolecule-fueled Molecular Machines; Acknowledgments
880-01/(S 3.8 Ammonium Cations and Structural Effects3.9 Photoresponsive Receptors; 3.9.1 Detecting Complexation Colorimetrically; 3.9.2 Detecting Complexation Fluorometrically; 3.10 Cation Transport; 3.10.1 Design of a Dynamic Cation Carrier; 3.10.2 Lariat Ethers; 3.10.3 Cation-π Interactions with Alkali Metal Cations; 3.11 Salt Complexation: Ditopic Receptors; 3.12 Pore-forming Amphiphiles; 3.12.1 A Cyclodextrin-based Channel; 3.12.2 Synthetic Amphiphilic Ionophores: Synthetic Ion Channels; 3.12.3 Hydraphile Biological Activity; 3.13 Future Challenges; References
2.7 Synthetic Receptors Derived from Combinatorial Techniques2.8 Dynamic Combinatorial Libraries for Receptor Discovery; 2.9 Cooperativity; 2.10 Entropy-Enthalpy Compensation; 2.11 Cross-reactive Arrays; 2.12 Conclusion; References; Chapter 3 Synthetic Receptors for Alkali Metal Cations; 3.1 Complexation of Alkali Metal Cations; 3.1.1 Coordination Complexes, Receptors, and Dynamics; 3.2 The Forces Involved in Complexation; 3.2.1 Enthalpy-Entropy Compensation; 3.2.2 Drawing Structural Conclusions from Binding Constants; 3.3 A Brief Overview of Complexation Constants
3.4 The Dynamics of the Complexation Process3.4.1 Solvent Effect on Complexation; 3.5 Crown Ethers and Related Receptor Types; 3.5.1 Crown Ethers; 3.5.2 Cryptands; 3.5.3 Spherands; 3.5.4 Calixarenes, Cavitands, and Other Complexing Agents; 3.6 Assessing Complexation; 3.6.1 Calorimetry; 3.6.2 Ion-selective Electrode Studies; 3.6.3 Salt Extraction and Colorimetry; 3.6.4 Comparison of Binding Assays; 3.6.5 Bulk Membrane Transport Rates; 3.6.6 Liposomal Membrane Studies; 3.7 Controlling Transport and Molecular Switching; 3.7.1 Redox Switching; 3.7.2 Photo-switched Transport
Chapter 4 Synthetic Receptors for Small Organic and Inorganic Anions
Summary An accessible overview of the most effective synthetic receptors within the context of specific applications
Bibliography ReferencesChapter 2 Design and Synthesis of Synthetic Receptors for Biomolecule Recognition; 2.1 The Foundations of Host-Guest Chemistry: Preorganization and Complementarity; 2.2 Strengths of Molecular Recognition Interactions; 2.3 Solvent Dependence of Binding Interactions; 2.4 Reversible Covalent Bonding; 2.5 From Plastic Models to Modern Computational Methods; 2.6 Common Synthetic Receptor Scaffolds; 2.6.1 Crown Ethers; 2.6.2 Calix[n]arenes; 2.6.3 Calix[n]pyrroles; 2.6.4 Cucurbit[n]urils; 2.6.5 Cyclodextrins; 2.6.6 Pinwheel Scaffolds
Notes English
Print version record
Subject Cell receptors -- Synthesis
Protein engineering.
Biomolecules.
Supramolecular chemistry.
Cell receptors.
Mathematical models.
Membrane proteins.
Proteins.
Models, Molecular
Receptors, Cell Surface
Models, Theoretical
Membrane Proteins
Investigative Techniques
Proteins
Analytical, Diagnostic and Therapeutic Techniques and Equipment
Amino Acids, Peptides, and Proteins
Chemicals and Drugs
Protein Engineering
mathematical models.
protein.
Biochemistry.
SCIENCE -- Life Sciences -- Biochemistry.
SCIENCE -- Chemistry -- General.
Supramolecular chemistry.
Biomolecules.
Protein engineering.
Form Electronic book
Author Anslyn, Eric
Gokel, George
Kubik, S
Wang, Binghe
Smith, Bradley D
Hong, Jong-In
Hargrove, A. E
Schmuck, C
Rotello, David
Royal Society of Chemistry (Great Britain), Content Provider.
ISBN 1849739714
9781849739719
9781782622062
1782622063
Other Titles Monographs in Supramolecular Chemistry